“…Therefore, fat grafting may be useful only in irradiated cases where there is little to no skin deficiency and the deformity is mild. 4 In addition, the theoretical risk of cancer and associated cancer screening requirements are controversial, particularly in breast-conserving surgery cases, because the mammary glands remain in situ and patients are believed to be prone to cancer recurrence. [26][27][28] Therefore, in the management of irradiated breast-conserving surgery cases with severe breast deformities, we suggest carefully considering the use of not only the Brava device but also fat grafting.…”