Evaluation of Clinical Signs and Tests of Congenital Dysplasia of the Hip

Kremli, Mamoun K.; Khoshhal, Khalid I.; Zamzam, Mohammed M.; Zamzani, Marwan; Badr, Abdulhalim A.; Taha, Wael

doi:10.5144/0256-4947.2002.102

Cited by 7 publications

(18 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In Saudi Arabia, a complete picture of the incidence pattern of DDH and the genotype–phenotype correlation is yet to emerge. Large number of cases still presenting late due to problems in early screening and diagnosis, and, hence, many of them need surgical intervention . The impact of this type of treatment compared with early conservative treatment on the patient, family and health services is great.…”

Section: Discussionmentioning

confidence: 99%

Developmental dysplasia of the hip: usefulness of next generation genomic tools for characterizing the underlying genes – a mini review

Basit¹,

Hannan²,

Khoshhal

2016

Clinical Genetics

View full text Add to dashboard Cite

Developmental dysplasia of the hip (DDH) is one of the most common skeletal anomalies. DDH encompasses a spectrum of the disorder ranging from minor acetabular dysplasia to irreducible dislocation, which may lead to premature arthritis in later life. Involvement of genetic factors underlying DDH became evident when several studies reported chromosomal loci linked to DDH in families with multiple affected individuals. Moreover, using association studies, variants in genes involved in chondrogenesis and joint formation have been shown to be associated with DDH. At least, one study identified a pathogenic variant in the chemokine receptor gene in DDH. No genetic analysis has been reported or carried out in DDH patients from the Middle East. Here, we review the literature related to genetics of DDH and emphasized the usefulness of new generation technologies in identifying genetic variants underlying DDH in consanguineous families.

show abstract

Section: Discussionmentioning

confidence: 99%

Developmental dysplasia of the hip: usefulness of next generation genomic tools for characterizing the underlying genes – a mini review

Basit¹,

Hannan²,

Khoshhal

2016

Clinical Genetics

View full text Add to dashboard Cite

show abstract

“…Highest incidence were reported from Finland, Croatia and Canada (5-195 per 1000), with very low incidences among populations in sub-Saharan Africa and Hong Kong (0-0.1 per 1000) [25]. Geographical and cultural factors regarding climate differences and the practice of swaddling respectively may in part explain this variation [26,27].…”

Section: Ethnicitymentioning

confidence: 98%

Diagnosis of Developmental Dysplasia of the Hip in Newborns and Infants

Padilla-Raygoza¹,

Flores-Vargas²,

Gallardo-Luna³

et al. 2022

Hip Replacement

View full text Add to dashboard Cite

It is a review of epidemiology data of development dysplasia of the hip; it was reviewed the pre pathogenic period: agent, host and environment and the role of risk factors for the presence of developmental dysplasia of the hip. What are the clinical data for the diagnosis; the sound transmission tests for the diagnosis of the developmental dysplasia of the hip. Also, the imaging procedures for the diagnosis of the same pathology.

show abstract

“…5 All newborns should be screened for DDH by neonatal hip screening physical examination. 6,7 If physical examination is doubtful or if there is an associated risk factor, ultrasonography should be used to confirm or exclude the diagnosis in children younger than 3 months and pelvic radiographs for older children. 8,9 The goal of DDH treatment is to obtain and maintain a safe concentric reduction of the hip in order to provide an optimal environment for the development of the femoral head and acetabulum, avoid avascular necrosis (AVN) and reduce the risk of early osteoarthrosis.…”

Section: Introductionmentioning

confidence: 99%