Evaluation of Clitoria ternatea L. Flower Extract in Preventing Complications of Diabetes Mellitus

Abstract

Diabetes mellitus type 2 (DM), a chronic metabolic condition, is now more common than ever globally. 1 Over the past three decades, DM patients have doubled. 2 Hyperglycemia, insulin resistance, and relative insulin deficiency are the characteristics of this disease. 1 A previous study found a high prevalence of glucose intolerance and undiagnosed DM in the population, highlighting the need for regular screening to reduce its incidence and complications in the short and long term. 3 The HbA1c test accurately measures chronic glycemic levels and assesses the risk of DM complications. 4 According to studies, oxidative stress, evidenced by high levels of biomarkers like MDA, has a significant impact on the development and complications of DM by encouraging lipid peroxidation, protein oxidation, and oxidative DNA damage. 5 Therefore, prevention and management of DM are critical to achieving therapeutic targets and preventing complications. 6