Evaluation of commercial microbial hydrocolloids concerning their effects on plasma lipids and caecal formation of SCFA in mice

Abstract

a b s t r a c tExopolysaccharides (EPS) are excreted by microorganisms into the surrounding environment and have been shown to have various physiological effects and are commonly used as food additives due to their rheological properties. Four commercially available microbial EPS with different polymeric structures and composition were tested in LDL receptor knock-out mice to investigate their effect on blood cholesterol, lipoproteins and caecal formation of SCFA. After four weeks on a Western diet supplemented with 4% EPS there were significant increases in caecal content and caecal tissue weight for the EPS groups compared to the control. The total pool of caecal short chain fatty acids was increased when mice were fed scleroglucan, xanthan and dextran. There were no differences in plasma cholesterol levels on the experimental diets compared to the control. Plasma triglycerides did not differ between groups. The results indicate that EPS supplementation to a Western diet may help in maintaining a healthy intestinal environment.

Effects of Pediococcus parvulus 2.6 and its exopolysaccharide on plasma cholesterol levels and inflammatory markers in mice

“…This effect of EPSs has been shown previously (Lindström et al 2012). The bulking effect was not shown by Pd 2.6 R probably due to the concentration of EPS being too low to impart a significant effect.…”

Antiobesity Effect of Exopolysaccharides Isolated from Kefir Grains

“…A significant reduction in body weight gain was found earlier in the EPS group compared to that in the other groups, including BG (positive control in viscosity) and Res groups. However, other EPS derived from different sources, including rice growth medium or EPS produced by a single lactic acid bacteria, did not affect body or adipose tissue weights. ,,− …”

Hypoglycemic and Hypolipidemic Effects of Glucomannan Extracted from Konjac on Type 2 Diabetic Rats

“…In addition, viscous dietary fiber supplementation has also been reported to inhibit cholesterol absorption in the jejunum and bile acid absorption in the ileum, which contribute to improvements in serum lipid regulation . Furthermore, consumption of viscous dietary fiber increased the relative abundance of probiotics, such as Bifidobacteria, Enterococcus, Lactobacillus, and Ruminococcus, as well as enhanced the short-chain fatty acids (SCFAs) in the colon, which has been identified to process various health-promoting functions. , However, with the increase of dietary fiber concentration, the gel-forming ability would increase and the water solubility would decrease. These two factors might cause the decreasing degree of SKGM fermentation .…”