Citrus green and blue mould, caused by Penicillium digitatum (PD) and P. italicum (PI), respectively, are mostly controlled by means of postharvest fungicide applications. Currently, IMZ is regarded as the most effective fungicide in use. Effective IMZ concentrations that inhibit 50% (EC 50 ) growth of nine PD and five PI isolates were assessed in vitro and the various isolates categorized according to their resistance (R) factors. Effective residue levels that provided 50% curative (ER 50 C) and protective (ER 50 P) control of these isolates were determined in vivo. All the PI isolates were sensitive, having EC 50 values of 0.005 -0.050 µg.mL -1 . Three PD isolates were sensitive (0.027 -0.038 µg.mL -1 ), while one resistant isolate was categorized as low resistant (Rfactor of 19), one as moderately resistant (R-factor of 33.2), three as resistant (R-factor of 50 -57.6) and one as highly resistant (R-factor of 70.7