Evaluation of current techniques of corneal epithelial removal in hyperopic photorefractive keratectomy

Griffith, May; Jackson, W. B.; Lafontaine, Marc D.; Mintsioulis, George; Agapitos, Peter J.; Hodge, William

doi:10.1016/s0886-3350(98)80100-4

Cited by 42 publications

(28 citation statements)

References 6 publications

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“…10,11 Chemical agents such as proparacaine 0.5%, iodine, cocaine, alkali n-heptanol, hypertonic saline solution, 12 and ethanol have been used to remove the corneal epithelium in experimental studies. Currently, 18% to 20% ethanol is commonly used in LASEK.…”

mentioning

confidence: 99%

Surface ablation techniques

Taneri

Weisberg

Azar

2011

Journal of Cataract and Refractive Surgery

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The ongoing quest for a safe, simple, effective, minimally invasive, and stable refractive surgical procedure to correct refractive errors has stimulated the development of surface ablation techniques and laser in situ keratomileusis. In this review, we describe the history, patient assessment, techniques, outcomes, and complications of surface ablation (photorefractive keratectomy, laser-assisted sub-epithelial keratectomy, epithelial laser-assisted in situ keratomileusis) and compare the results of various surface techniques. Surface ablation procedures will continue to evolve, with potential improvements in outcomes accompanying future sophisticated ablation profiles and laser technology.

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confidence: 99%

Surface ablation techniques

Taneri

Weisberg

Azar

2011

Journal of Cataract and Refractive Surgery

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“…3,4 Several techniques of epithelial debridement have been tried with PRK-type surgery including mechanical debridement, laser transepithelial ablation, a rotating brush, and alcohol debridement. [5][6][7][8][9][10] In addition, other variations of surface ablation laser vision correction have arisen, such as laser-assisted subepithelial keratectomy (LASEK) and advanced surface ablation (ASA), to create and/or market less painful or more efficient surgery. 7,8,[11][12][13][14] Advanced surface ablation is similar to PRK, in which epithelial debridement is aided by the use of 18% ethyl alcohol instead of the traditional mechanical debridement used with PRK.…”

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confidence: 99%

Comparison of postoperative pain in patients following photorefractive keratectomy versus advanced surface ablation

Blake

Cervantes-Castañeda

Macías-Rodríguez

et al. 2005

Journal of Cataract and Refractive Surgery

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Advanced surface ablation was associated with statistically significantly more postoperative pain than PRK on postoperative day 1. A greater percentage of patients reported more pain in the advanced surface ablation-treated eyes on day 3. Refractive surgeons should consider the postoperative pain associated with advanced surface ablation when deciding on the type of epithelial debridement for their patients.

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“…The presence of residual epithelial cells and Bowman membrane in PRK probably accounts for the greater fluorescence signal than with LASIK. 11,12 Also, although both brush PRK and ethanol PRK completely remove epithelial cells centrally, a greater amount of residual peripheral cells may be present after brush PRK than after ethanol PRK, which may explain the additional fluorescent UV scatter seen in brush PRK. The minimum recorded UV scatter was similar between all 3 procedures, with a greater standard deviation in both the brush PRK and ethanol PRK groups, supporting this hypothesis.…”

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confidence: 99%