Evaluation of Cytology and Colposcopy in the Follow up of Laser Ablation for Cervical Intra-Epithelial Neoplasia

Arena, Bruno; Valentine, B. H.

doi:10.3109/01443619109027825

Cited by 2 publications

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“…Recent studies that have attempted evaluation of post treatment follow up methods vary in their conclusions regarding the place of routine, as compared with selective, colposcopic review. Two studies recommended abandoning routine colposcopic assessment following laser vaporisation (Giles et al 1989; Lopes et al 1990), whilst two expressed reservations on the safety of this policy (Arena & Valentine 1991; Paraskevaides et al 1991).…”

Section: Discussionmentioning

confidence: 99%

The value of cytology and colposcopy in the follow up of cervical intraepithelial neoplasia after treatment by laser excision

Mahadevan

Horwell

1993

BJOG

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Objective To determine the value of colposcopic assessment in the follow up of cervical intraepithelial neoplasia (CIN) treated by laser excision. Design Retrospective analysis of case records of women with CIN treated by laser excision over the period 1986 to 1990. Setting A colposcopy clinic in a district general hospital. Subjects Five hundred‐forty consecutive patients with either CIN or microinvasion diagnosed on laser excision specimens. Results Of 452 patients followed up for 10 months, 14 were diagnosed as having persistent CIN. Eleven of these were detected at the first follow up visit at four months using both colposcopic and cytological assessment. Elimination of colposcopic assessment in follow up would have reduced the number detected to five patients. Conclusion For patients undergoing laser excision for CIN involving the endocervical canal, a normal initial, post‐treatment colposcopy is necessary before surveillance may be reduced to cytology alone.

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Section: Discussionmentioning

confidence: 99%

The value of cytology and colposcopy in the follow up of cervical intraepithelial neoplasia after treatment by laser excision

Mahadevan

Horwell

1993

BJOG

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“…Several studies have attempted to determine the role of colposcopy, but the numbers studied have usually been too small to allow firm conclusions to be drawn as most described less than 30 recurrences 3–7 . The three studies with larger numbers of recurrences reported sensitivity rates for cytology of 60, 82 and 63% 8–10 . All three recommended the inclusion of colposcopy in follow up but gave no data on specificity.…”

Section: Introductionmentioning

confidence: 99%

Gynaecological oncology: The role of colposcopy in the follow up of women treated for cervical intraepithelial neoplasia

Soutter

Butler

Tipples

2006

BJOG

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Objective To determine the effect of colposcopy on the sensitivity and specificity of follow-up procedures in the detection of residual or recurrent disease after treatment for cervical intraepithelial neoplasia (CIN).Design A retrospective study of information held in a colposcopy database.Setting A teaching hospital colposcopy clinic. Main outcome measures The sensitivity and specificity of cytology alone was compared with the sensitivity and specificity of the combination of colposcopy and cytology.Results Colposcopy improved the sensitivity of cytology for the detection of high-grade disease from 64 to 91% but reduced the specificity from 95 to 88%. With a 3% rate of post-treatment highgrade disease, colposcopy detected 8 extra cases per 1000 women but resulted in 88 more false alarms per 1000 women. Among women in whom the treatment margins were involved or uncertain, colposcopy detected 13 extra cases per 1000 women but resulted in 12 fewer false alarms per 1000 women because the prevalence of post-treatment disease was higher.Conclusions Colposcopy does improve the detection rate of posttreatment disease but at a cost of additional false alarms. The benefit of colposcopy will be greater in high-risk groups of women with higher rates of treatment failure.Keywords CIN, colposcopy, cytology, recurrence, sensitivity.Please cite this paper as: Soutter W, Butler J, Tipples M. The role of colposcopy in the follow up of women treated for cervical intraepithelial neoplasia. BJOG 2006; 113:511-514.

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Evaluation of Cytology and Colposcopy in the Follow up of Laser Ablation for Cervical Intra-Epithelial Neoplasia

Cited by 2 publications

References 4 publications

The value of cytology and colposcopy in the follow up of cervical intraepithelial neoplasia after treatment by laser excision

The value of cytology and colposcopy in the follow up of cervical intraepithelial neoplasia after treatment by laser excision

Gynaecological oncology: The role of colposcopy in the follow up of women treated for cervical intraepithelial neoplasia

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