Evaluation of deployment capability of a novel outside-the-scope, detachable catheter system for ablation of lung lesions in ex vivo human lung models

Huseini, Taha; Söder, Stephan; Katz, Amit; Mihalik, Teresa; Liberman, Moïshe; Ferraro, Pasquale; Lafontaine, Edwin; Martin, Jocelyne; Nasir, Basil S.

doi:10.1016/j.xjtc.2022.07.009

Cited by 2 publications

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, new tools are being developed such as an outside-the-scope catheter system with which the cryoprobe is attached outside the bronchoscope via an external working channel and can be removed free from the bronchoscope providing real-time visualization of the airway. This may hold promise for increasing procedural safety and minimizing bleeding-related complications [ 76 ]. With advancements in cancer therapies which ideally require a maximum volume of tissue for genotyping and phenotyping, TBCB may be considered the first-line tool for the diagnosis of lung cancer.…”

Section: Contraindicationsmentioning

confidence: 99%

Utility and Safety of Bronchoscopic Cryotechniques—A Comprehensive Review

Husnain,

Sarkar,

Huseini

2023

Diagnostics

Self Cite

View full text Add to dashboard Cite

Cryosurgical techniques are employed for diagnostic and therapeutic bronchoscopy and serve as important tools for the management of pulmonary diseases. The diagnosis of interstitial lung disease requires multidisciplinary team discussions after a thorough assessment of history, physical exam, computed tomography, and lung-function testing. However, histological diagnosis is required in selected patients. Surgical lung biopsy has been the gold standard but this can be associated with increased morbidity and mortality. Transbronchial lung cryobiopsy is an emerging technique and multiple studies have shown that it has a high diagnostic yield with a good safety profile. There is wide procedural variability and the optimal technique for cryobiopsy is still under investigation. There is emerging data that demonstrate that cryobiopsy is safe and highly accurate in the diagnosis of thoracic malignancies. Furthermore, cryorecanalization procedures are a useful adjunct for the palliation of tumors in patients with central airway obstruction. One should keep in mind that these procedures are not free from complications and should be carried out in a specialized center by a trained and experienced bronchoscopy team. We present a review of the literature on the diagnostic and therapeutic utility of bronchoscopy-guided cryosurgical procedures and their safety profile.

show abstract

Section: Contraindicationsmentioning

confidence: 99%