Evaluation of depressive symptoms in patients with coronary artery disease using the Montgomery Åsberg Depression Rating Scale

Abstract

The aim of this study was to evaluate, in patients with coronary artery disease (CAD), factor structure and psychometric properties of the Montgomery Åsberg Depression Rating Scale (MADRS) to identify patients with current major depressive episode (MDE). The construct validity of the MADRS against self-rating scales was also evaluated. Consecutive 522 CAD patients at admission to the cardiac rehabilitation program were interviewed for the severity of depressive symptoms using the MADRS and for current MDE using the structured MINI International Neuropsychiatric Interview. Also, all patients completed the Hospital Anxiety and Depression Scale and the Beck Depression Inventory-II. The MADRS had one-factor structure and high internal consistency (Cronbach's coefficient α=0.82). Confirmative factor analysis indicated an adequate fit: comparative fit index=0.95, normed fit index=0.91, and root mean square error of approximation=0.07. At a cut-off value of 10 or higher, the MADRS had good psychometric properties for the identification of current MDE (positive predictive value=42%, with sensitivity=88% and specificity=85%). There was also a moderate to strong correlation of MADRS scores with scores on self-rating depression scales. In sum, in CAD patients undergoing rehabilitation, the MADRS is a unidimensional instrument with high internal consistency and can be used for the identification of depressed CAD patients. The association between MADRS and self-rating depression scores is moderate to strong.

Association of work-related stress with mental health problems in a special police force unit

“… BDI, Beck Depression Inventory43 44; BFQ, Big Five Questionnaire38 39; DCS, Demand–Control–Support Questionnaire16 40; ERI, Effort–Reward–Imbalance Questionnaire17 40; M, mean; MBI, Maslach Burnout Inventory50 51; STAI-T, State-Trait Anxiety Inventory-Trait 48 49 …”

“…Depression was evaluated by the Beck Depression Inventory (BDI),43 as this questionnaire proved to be effective for depression screening 44 45. The BDI consists of 21 groups of four alternative self-evaluation statements used to assess the presence and severity of the affective, cognitive, motivational, psychomotor and vegetative components of depression, with higher scores indicating more severe depression.…”

“…The cut-off score commonly used in clinical practice for depression screening is 10 46. The probability of suffering major depressive disorder rapidly increases above this threshold, so a higher score of 1444 or 1645 is often chosen in order to reduce the prevalence of false positive in populations consisting of patients affected by chronic diseases with poor or severe prognosis. In this study, we adopted the classical cut-off level of 10, as the participants tested were young, active and highly selected.…”

Depression in Adults with Attention-Deficit/Hyperactivity Disorder (ADHD): The Mediating Role of Cognitive-Behavioral Factors

“…The MADRS is a valid measure (Müller et al 2003), highly correlated with the Hamilton Depression Rating Scale ( r = .94), the Research Diagnostic Criteria for depression ( r = .70), and the Inventory of Depressive Symptomology- Clinician Rated ( r = .81). The MADRS is also a reliable measure, with high inter-rater reliability (κ = .89–.97) and internal consistency (α = .82) (Bunevicius et al 2012; Cusin et al 2010; Montgomery and Asberg 1979). Internal consistency of both the AISRS and MADRS in this sample was good (α = .84–.85).…”

Validity of Beck Depression Inventory for the assessment of depressive mood in chronic heart failure patients

“…In patients with CAD, moderate to strong correlations between MADRS scores and self-rating depression score (BDI-II and HAD) have already been found (Bunevicius et al, 2012a(Bunevicius et al, , 2012b.…”