Evaluation of Diastolic Heart Function Using Echocardiography and Pulse Wave Analysis in Patients After Anthracycline Therapy

Sudakova, Magdalena; Budinskaya, Ksenia; Nováková, Zuzana

doi:10.23919/cinc53138.2021.9662816

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…SVI could be used as an indicator of the effectiveness of myocardial oxygenation, which occurs exclusively during the diastole, and changes in this parameter imply possible predispositions of the left ventricle to diastolic dysfunction. Moreover, SVI can be used to predict even subclinical changes of the myocardial tissue [ 40 ]. Our respondents showed significantly higher SVI after their one-month long stay in the children’s hospital.…”

Section: Discussionmentioning

confidence: 99%

Changes in Nutritional State and Cardiovascular Parameters in Alimentary Obese Children after a Month-Long Stay in Children’s Treatment Center

et al. 2022

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Childhood and adolescent obesity has become an important public health issue, as it leads to higher risk of cardio–metabolic, orthopedic, and psychological comorbidities. The aim of this study was to evaluate the changes in nutritional state and cardiovascular system parameters in obese children. Sixty respondents aged 9–17 years with alimentary obesity participated in this research. Anthropometric parameters (body weight (BWT), body mass index (BMI), percentage of body fat (%), waist and hip circumference (WC and HC), waist–hip ratio (WHR)) and cardiovascular parameters (systolic and diastolic blood pressure (SP and DP), cardio-ankle vascular index (CAVI), ankle-brachial index (ABI), pulse wave velocity and its variability (PWV and PWVV), and parameters of pulse wave analysis) were measured. Every respondent went through two sets of measurements, the first (I.) after their admission to the children’s hospital and the second (II.) at the end of their one-month-long therapeutic stay. Statistically significant differences between measurements I. and II. were observed in the following parameters: BWT (p < 0.01), BMI (p < 0.01), WC (p < 0.01), HC (p < 0.01), DP (p < 0.01), PWV (p < 0.05), and ABI (p < 0.01). The results of this study show that obesity has a mostly negative impact on the cardiovascular health of affected children, with likely negative results in their adulthood.

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Section: Discussionmentioning

confidence: 99%

Changes in Nutritional State and Cardiovascular Parameters in Alimentary Obese Children after a Month-Long Stay in Children’s Treatment Center

et al. 2022

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Effects of Peroral Hormonal Contraception on Cardiovascular System: Analysis of Selected Cardiovascular Parameters in an Adolescent Cohort; a Pilot Project

2022

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Oral contraceptive pills (OCPs) have some strong advantages over more traditional types of contraception, including their consistently high contraceptive effect as well as multiple additional positive side effects. OCPs went through decades of intense pharmaceutical development and current formulas are well optimized – however, a handful of their negative side effects remain, including some that affect cardiovascular system, for example higher risk of hypertension, venous thromboembolism and increased arterial stiffness. The gold standard for arterial stiffness assessment is currently applanation tonometry, a method that relies on arterial pulse wave velocity measurement (PWV). Another possible method for arterial stiffness measurement is the use of the VaSera device, which measures cardio-ankle vascular index (CAVI). The aim of this study was to discover the effect of OCPs use on selected cardiovascular parameters related to arterial stiffness. We measured these cardiovascular parameters in the OCPs using group (OCP) and in the control group (CTRL) using applanation tonometer Sphygmocor and the VaSera device. Comparison of the data from both groups showed us significantly increased diastolic blood pressure (DBP) and carotid-radial pulse wave velocity (crPWV) as well as significantly lower subendocardial viability index (SVI) in the OCP. These results imply a negative effect of hormonal contraceptives on the cardiovascular system with most of the negative changes affecting the peripheral arteries. Despite this evidence supporting the hypothesis of OCPs having a negative effect on cardiovascular health, further research is necessary.

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Evaluation of Diastolic Heart Function Using Echocardiography and Pulse Wave Analysis in Patients After Anthracycline Therapy

Cited by 2 publications

References 8 publications

Changes in Nutritional State and Cardiovascular Parameters in Alimentary Obese Children after a Month-Long Stay in Children’s Treatment Center

Changes in Nutritional State and Cardiovascular Parameters in Alimentary Obese Children after a Month-Long Stay in Children’s Treatment Center

Effects of Peroral Hormonal Contraception on Cardiovascular System: Analysis of Selected Cardiovascular Parameters in an Adolescent Cohort; a Pilot Project

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