Introduction/Objective. The correct choice of local anesthesia should
consider the simplest technique to perform, with maximum anesthesia and
minimal discomfort for the patient. The objectives of this research were to
determine the efficacy of the modified in comparison to the standard
Vazirani-Akinosi technique and to compare techniques regarding clinically
relevant parameters. Methods. The research was conducted at the Clinic for
Oral Surgery, School of Dental Medicine, University of Belgrade. A
prospective, randomized, single-blinded clinical trial included sixty
patients scheduled for surgical extraction of mandibular third molars. The
first group of patients was anesthetized using mVAt, while the second group
received anesthesia using VAt. Pain during injection, onset time, duration
of anesthesia, and width of the anesthetized area were evaluated parameters.
Results. Out of 60 performed injections, 42 were successful, which proved
to be statistically significant in comparison to 18 unsuccessful injections
(p = 0.047). The failure rate of BN anesthesia was statistically
significantly lower in mVAt group (p = 0.030). There was no statistically
significant difference among groups considering pain (p = 0.114), onset time
(p = 0.370) and duration of anesthesia (p = 0.628). Conclusion. Modified VA
technique proved to be more successful regarding BN anesthesia. Considering
other examined clinical parameters, both techniques showed similar
performance.