2020
DOI: 10.1007/s10238-020-00643-2
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Evaluation of different proton pump inhibitors combined with bismuth quadruple regimens in Helicobacter pylori eradication

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Cited by 3 publications
(5 citation statements)
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“…The PPI potency has a strong ability to reliably maintain a relatively high intragastric pH. A previous study evaluating the efficacy of different PPIs combined with bismuth quadruple regimens for H. pylori eradication demonstrated that the eradication rates between different PPI regimens were similar in treating H. pylori infection ( Kan et al, 2020 ). To achieve a reliable cure rate, a high dose of PPI that is unaffected by CYP2C19 genotypes may be needed.…”
Section: Discussionmentioning
confidence: 99%
“…The PPI potency has a strong ability to reliably maintain a relatively high intragastric pH. A previous study evaluating the efficacy of different PPIs combined with bismuth quadruple regimens for H. pylori eradication demonstrated that the eradication rates between different PPI regimens were similar in treating H. pylori infection ( Kan et al, 2020 ). To achieve a reliable cure rate, a high dose of PPI that is unaffected by CYP2C19 genotypes may be needed.…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, in areas with high drug resistance rate, the best solution for H. pylori eradication is anti‐ H. pylori therapy containing bismuth (Dore et al, 2016; W. Z. Liu et al, 2018). In a recent study, we found that the quadruple regimen containing PPI, colloid pectin bismuth, amoxicillin, and furazolidone for 14 days had a significant high eradication effect on H. pylori , among which the eradication rate of the regimen combined with pantoprazole (one kind of PPI) was over 90% (Kan et al, 2020). The quadruple therapy contains more drugs than triple therapy, which may mean more ADR during medication.…”
Section: Treatment Strategies For H Pylori Infectionmentioning
confidence: 99%
“…Both amoxicillin and furazolidone were the antibiotics recommended for the first‐line quadruple regimens in China (W. Z. Liu et al, 2018). Quality clinical feedback was obtained based on the H. pylori treatment management recommendation (Kan et al, 2020). It is necessary to guide the treatment regimens in clinical to follow the recommendations from the guidelines as well as the expert consensus.…”
Section: Introductionmentioning
confidence: 99%
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“…Так, у 1410 Н. pylori-позитивных больных сравнивали эффективность, а также экономичность 4 схем, включавших в себя квадротерапию с препаратами висмута и различные ИПП: пантопразол в капсулах с кишечнорастворимой оболочкой (группа А, 352 пациента), эзомепразол в таблетках с кишечнорастворимой оболочкой (группа В, 462 пациента), пантопразол в таблетках с кишечнорастворимой оболочкой (группа С, 392 пациента) и рабепразол в таблетках с кишечнорастворимой оболочкой (группа D, 204 пациента). Частота эрадикации в этих группах составила соответственно 91,48, 89,83, 86,73 и 90,69% и достоверно не различалась (р > 0,05), хотя в группе больных, получавших пантопразол в капсулах, она была наиболее высокой, а стоимость лечениянаиболее низкой [18].…”
Section: пантопразол в лечении язвенной болезни а также профилактике ...unclassified