Evaluation of early postoperative morbidity in pediatric tonsillectomy with the use of sucralfate

Sampaio, André Luiz Lopes; Pinheiro, Thaís Gonçalves; Furtado, Paula Lobo; Araújo, Mercêdes F. S.; Olivieira, Carlos A.C.P.

doi:10.1016/j.ijporl.2006.12.016

Cited by 26 publications

(36 citation statements)

References 22 publications

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“…). Although designed for children aged 3–12 years to self‐report their pain, OUCHER has been used by observers (medical staff and parents) to assess pain intensity in infants aged 7–38 weeks after immunisation and in children aged 3–12 years after tonsillectomy …”

Section: Methodsmentioning

confidence: 99%

“…Although designed for children aged 3-12 years to self-report their pain, OUCHER has been used by observers (medical staff and parents) to assess pain intensity in infants aged 7-38 weeks after immunisation 10 and in children aged 3-12 years after tonsillectomy. 11 Participant baseline FLACC and OUCHER scores were recorded by the participant's parent/guardian(s), the doctor performing the TUBC and the nurse assisting before commencement of the TUBC.…”

Section: Study Outcomesmentioning

confidence: 99%

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Oral sucrose for analgesia in children aged between 3 months and 3 years undergoing transurethral bladder catheterisation: A randomised, double‐blinded, clinical trial

London

Watson

Kwok

et al. 2019

J Paediatrics Child Health

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Aim Many children admitted to hospital undergo invasive, painful and stressful procedures, including children who are not toilet trained undergoing transurethral bladder catheterisation (TUBC). Oral sucrose is commonly given to children to reduce procedural pain. In this study, we evaluated the effectiveness of oral sucrose in reducing procedural pain in children aged between 3 months and 3 years undergoing TUBC. Methods This study was a randomised, double‐blind, placebo‐controlled study conducted at Nepean Hospital, Sydney, Australia from June 2005 to June 2010. A total of 40 participants requiring TUBC for diagnostic evaluation were included. The participants were randomly assigned to receive 4 mL of 75% oral sucrose (n = 20) or a placebo (sterilised water) (n = 20). The primary outcomes were changes in two paediatric pain scale scores (the FLACC pain scale and the OUCHER pain scale), assessed by the parent/guardian(s), the doctor performing the TUBC and the nurse assisting. The secondary outcomes were physiological (changes in heart rate) and behavioural pain (crying) indicators. Results Of the outcome measures, 65% favoured the oral sucrose group, 31% favoured the placebo group, and 4% found no difference between the oral sucrose and placebo groups. Conclusion While the trends favouring the sucrose group in this study were encouraging, as the results were not statistically significant, there was insufficient evidence to demonstrate the effectiveness of oral sucrose in reducing procedural pain in children aged between 3 months and 3 years undergoing TUBC.

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Section: Methodsmentioning

confidence: 99%

Section: Study Outcomesmentioning

confidence: 99%

Oral sucrose for analgesia in children aged between 3 months and 3 years undergoing transurethral bladder catheterisation: A randomised, double‐blinded, clinical trial

London

Watson

Kwok

et al. 2019

J Paediatrics Child Health

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“…In these patients, reduction of postoperative pain must be the most important goal of the clinician. There are some drugs used before, during or after the procedure to reduce postoperative pain after tonsillectomy [7][8][9][10][11]. Systemic paracetamol and non steroid antiinflamatory drugs are the most commonly used drugs for analgesia.…”

Section: Introductionmentioning

confidence: 99%

“…Sucralfate is an agent used in the treatment of peptic ulcer. It is believed to provide a protective barrier by its tendency to bind to exposed protein of the ulcer [9,10]. Also, there is evidence that sucralfate promotes local production of prostaglandin E2, thus increasing blood flow, mucous production, mitotic activity, and surface migration of cells.…”

Section: Introductionmentioning

confidence: 99%

“…Pain after tonsillectomy is caused by the pharyngeal muscles spasm and inflammation and irritation of nerve endings. It continues until the exposed and inflamed muscles become covered with a regenerated mucous membrane [8,9].Sucralfate may provide a protective coating on surfaces of pharyngeal muscles and prevent from muscle spasm and irritation of open nerve endings. This study was designed to evaluate the efficacy of sucralfate in the management of pain after tonsillectomy during the first seven days and in return to normal diet time and return to regular daily activities time.…”

Section: Introductionmentioning

confidence: 99%

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Use of Topical Sucralfate in the Management of Postoperative Pain After Tonsillectomy

Özler¹

2014

Eu Clin Anal Med

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Bu çalışmanın amacı tonsillektomi sonrası ağrı yönetimi, normal diyete dönüş zamanı ve günlük aktivitelere dönüş zamanı açısından sükralfatın etkinliğini değerlendirmektir. Gereç ve Yöntem: Soğuk bıçak tonsillektomi yapılan 8 yaş üstü 60 hasta rasgele sükralfat(SUK)(n=30) ve kontrol grubu(n=30) olarak iki gruba ayrıldı. Hastalar boğaz ağrısı, yutma güçlüğü ve kulak ağrısı açısından postoperatif ilk 7 gün günde bir kez değerlendirildi. Hastalar ayrıca normal diyete dönüş zamanı ve günlük aktivitelere dönüş zamanı açısından da değerlendirildi. Bulgular: Ortalama boğaz ağrısı, yutma güçküğü ve kulak ağrısı skorları postoperatif 7 gün boyunca SUK grubunda anlamlı düzeyde daha düşük olarak saptandı (p<0.05). Ortalama normal diyete dönüş zamanı ve günlük aktivitelere dönüş zamanı kontrol grubunda SUK grubuna göre daha geç olarak saptandı (p=0.0001). Tartışma: Bu bilgiler ışığında, topical sükralfat tonsillektomi sonrası semptomları azaltma açısından etkin, güvenilir ve iyi tolere edilebilen bir ajan olarak önerilebilir.

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Effect of Topical Sucralfate vs Clindamycin on Posttonsillectomy Pain in Children Aged 6 to 12 Years

Jahanshahi

Pazira

Farahani

et al. 2014

JAMA Otolaryngol Head Neck Surg

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Evaluation of early postoperative morbidity in pediatric tonsillectomy with the use of sucralfate

Cited by 26 publications

References 22 publications

Oral sucrose for analgesia in children aged between 3 months and 3 years undergoing transurethral bladder catheterisation: A randomised, double‐blinded, clinical trial

Oral sucrose for analgesia in children aged between 3 months and 3 years undergoing transurethral bladder catheterisation: A randomised, double‐blinded, clinical trial

Use of Topical Sucralfate in the Management of Postoperative Pain After Tonsillectomy

Effect of Topical Sucralfate vs Clindamycin on Posttonsillectomy Pain in Children Aged 6 to 12 Years

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