Evaluation of early visual recovery in pituitary macroadenomas after endoscopic endonasal transphenoidal surgery: Quantitative assessment with diffusion tensor imaging (DTI)

Anık, İhsan; Anık, Yonca; Koç, Kenan; Ceylan, Savaş; Genç, Hülya Maraş; Altıntaş, Özgül; Özdamar, Dilek; Ceylan, D.

doi:10.1007/s00701-011-0942-4

Cited by 55 publications

(33 citation statements)

References 23 publications

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“…Meanwhile, FA has a negative correlation with visual parameters in the optic nerves [17]. Additionally, several quantitative studies indicate that FA may be correlated with glaucoma severity [18], [19].…”

Section: Introductionmentioning

confidence: 98%

Alteration of Fractional Anisotropy and Mean Diffusivity in Glaucoma: Novel Results of a Meta-Analysis of Diffusion Tensor Imaging Studies

Huang

et al. 2014

PLoS ONE

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ObjectivesWe hypothesized that a meta-analysis of existing studies may help to reveal significant changes on diffusion tensor imaging (DTI) in patients with glaucoma. Therefore, a meta-analysis was utilized to investigate the possibility that DTI can detect white matter damage in patients with glaucoma.MethodsThe study design and report adhered to the PRISMA Statement guidelines. DTI studies that compared glaucoma patients and controls were surveyed using PubMed, Web of Science and EMBASE (January 2008 to September 2013). Stata was used to analyze the decrease in fractional anisotropy (FA) and increase in mean diffusivity (MD) in the optic nerve and optic radiation in patients with glaucoma.ResultsEleven DTI studies were identified through a comprehensive literature search, and 10 independent DTI studies of glaucoma patients were eligible for the meta-analysis. A random effects model revealed a significant FA reduction in the optic nerve and optic radiation, as well as a significant MD increase in the tracts. A heterogeneity analysis suggested that FA may be related to glaucoma severity.ConclusionsOur findings revealed that the optic nerve and optic radiation were vulnerable regions in patients with glaucoma and that FA may be correlated with glaucoma severity and age. Furthermore, this study suggests that magnetic resonance imaging in patients with glaucoma may help to provide objective evidence to aid in the diagnosis and management of glaucoma.

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Section: Introductionmentioning

confidence: 98%

Alteration of Fractional Anisotropy and Mean Diffusivity in Glaucoma: Novel Results of a Meta-Analysis of Diffusion Tensor Imaging Studies

Huang

et al. 2014

PLoS ONE

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“…Three dimensional (3D) tractography of the entire human visual system might be more useful in preoperative and/or intraoperative neurosurgical planning to preserve structural integrity and avoid visual field defects by mapping the optic radiations [38, 39] as well as for quantitative assessment of visual recovery after surgery [3, 40, 41, 42, 43, 44] or in congenital lesions [45, 46]. …”

Section: Introductionmentioning

confidence: 99%

Distinguishing and quantification of the human visual pathways using high-spatial-resolution diffusion tensor tractography

Kamali¹,

Hasan²,

Adapa

et al. 2014

Magnetic Resonance Imaging

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Quantification of the living human visual system using MRI methods has been challenging, but several applications demand a reliable and time-efficient data acquisition protocol. In this study, we demonstrate the utility of high spatial resolution diffusion tensor fiber tractography (DTT) in reconstructing and quantifying the human visual pathways. Five healthy males, age range 24–37 years, were studied after approval of the Institutional Review Board (IRB) at The University of Texas Health Science Center at Houston. We acquired diffusion tensor imaging (DTI) data with 1-mm slice thickness on a 3.0 Tesla clinical MRI scanner and analyzed the data using DTT with the fiber assignment by continuous tractography (FACT) algorithm. By utilizing the high spatial resolution DTI protocol with FACT algorithm, we were able to reconstruct and quantify bilateral optic pathways including the optic chiasm, optic tract, optic radiations free of contamination from neighboring white matter tracts.

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“…A spherical balloon representing a growing tumour was inflated first and then translated inferiorsuperiorly so as to elevate and compress the chiasm from below ( Figure 1). Inspection of the MRI scans of patients experiencing chiasmal compression [13][14][15] indicates that it is reasonable to ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 5 use an initially-spherical balloon to represent the tumour. Micro-scale models were subsequently generated using RVE to investigate the strain distributions within nerve fibres.…”

Section: Methodsmentioning

confidence: 99%

Biomechanics of chiasmal compression: Sensitivity of the mechanical behaviors of nerve fibers to variations in material property and geometry

Wang

Neely

McIlwaine

et al. 2016

International Journal for Computational Methods in Engineering

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The mechanism of bitemporal hemianopia is still unclear. Previous research suggested that the nerve fibre packing pattern may contribute to the selective damage of nasal (crossed) nerve fibres. Numerical models were built using finite element modelling to study the biomechanics of optic nerve fibres. The sensitivity of the mechanical behaviours of the nerve fibres to variations of five parameters in the nerve fibre model were investigated using design of experiments (DOE). Results show that the crossing angle is a very significant factor that affects a wide range of responses of the model. The strain difference between the crossed and the uncrossed nerve Downloaded by [University of Cambridge] at 06:51 05 June 2016 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 2 fibres may account for the phenomenon of bitemporal hemianopia. This work also highlights the need for more accurate material properties of the tissues in the model and an improved understanding of the microstructure of the optic chiasm.

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Evaluation of early visual recovery in pituitary macroadenomas after endoscopic endonasal transphenoidal surgery: Quantitative assessment with diffusion tensor imaging (DTI)

Abstract: There is a correlation between DTI-derived FA values of the optic nerves and visual parameters. DTI assessments of the affected sides with FA and MD values may help to estimate the response of visual improvement to the surgical therapy in the early postoperative period.

Cited by 55 publications

References 23 publications

Alteration of Fractional Anisotropy and Mean Diffusivity in Glaucoma: Novel Results of a Meta-Analysis of Diffusion Tensor Imaging Studies

Alteration of Fractional Anisotropy and Mean Diffusivity in Glaucoma: Novel Results of a Meta-Analysis of Diffusion Tensor Imaging Studies

Distinguishing and quantification of the human visual pathways using high-spatial-resolution diffusion tensor tractography

Biomechanics of chiasmal compression: Sensitivity of the mechanical behaviors of nerve fibers to variations in material property and geometry

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