Evaluation of Effects of Application of a Citroxain‐Containing Dentifrice

Lyon, Thayer C.; Parker, Warren A.; Barnes, George P.

doi:10.1111/j.1708-8240.1991.tb00809.x

Cited by 15 publications

(6 citation statements)

References 3 publications

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“…The present study showed that the mean Lightness value of test group after brushing was significantly higher than that of the control group. Similar results were reported by Lyon Jr (1991) (12) with Citroxain (mixture of papaya, alumina and sodium citrate) containing dentifrice (Rembrandt) using a customized shade guide. The test dentifrice in the present study contained extracts of papain and bromelain, which are proteolytic enzymes.…”

Section: Discussionsupporting

confidence: 85%

Stain removal efficacy of a novel dentifrice containing papain and Bromelain extracts - an in vitro study

Kalyana

Shashidhar

Meghashyam

et al. 2010

International Journal of Dental Hygiene

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Section: Discussionsupporting

confidence: 85%

Stain removal efficacy of a novel dentifrice containing papain and Bromelain extracts - an in vitro study

Kalyana

Shashidhar

Meghashyam

et al. 2010

International Journal of Dental Hygiene

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“…Clinical studies using toothpaste containing a mixture of papain, alumina and sodium citrate (Rembrandt) have also reported a significant stain removal. [7–9] The test dentifrice in the present study contained extracts of papain and bromelain, which are proteolytic enzymes. They disrupt and ⁄ or remove the protein portion of the pellicle ⁄ plaque layer that forms on the surface of teeth over time, thus removing the stains that are bound to these proteins.…”

Section: Discussionmentioning

confidence: 99%

“…[6] Clinical studies have demonstrated the stain removal efficacy of dentifrice containing papain, alumina and sodium citrate. [7–9] Recently an in vitro study reported that a papain and bromelain (proteolytic enzymes) containing dentifrice was more effective in removing stains than the control dentifrice. [10]…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts

Pentapati¹,

Acharya²

2012

Journal of Young Pharmacists

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To evaluate the stain removal efficacy of a novel dentifrice containing papain and bromelain extracts (Glodent) in comparison with a control dentifrice (Colgate regular). This was a randomized, positive-controlled, double-blinded, clinical study. Subjects were randomly divided into one of the two study groups. Pre-treatment and post treatment photographs of the 4 anterior teeth were recorded under standardized conditions and analyzed for lightness or luminosity values using Adobe Photoshop. The difference between the mean pre-treatment luminosity of test and control groups was not statistically significant. In both test and control groups, the post-treatment luminosity was significantly higher than pre- treatment luminosity (P < 0.001 and P = 0.003 respectively). The mean post-treatment luminosity for test group was found to be significantly higher than control group. The mean percentage removal of stains for test group was significantly higher than control group. The test dentifrice showed significant stain removal when compared to control which could be attributed to the role of proteolytic enzymes in the test dentifrice.

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“…81 More recently, a toothpaste containing a mixture of the protease enzyme papain, alumina and sodium citrate has been described in the literature. Although an early clinical study showed no significant effect of this toothpaste on removing established extrinsic stain versus a placebo toothpaste, 82 further clinical studies have demonstrated the combination toothpaste to be effective at removing established stains, 83 more effective at removing established extrinsic stain than a tartar control toothpaste, 84 and more effective at removing chlorhexidine induced stain than a control toothpaste. 85 Phosphate materials, such as pyrophosphate, tripolyphosphate and hexametaphosphate, tend to have a strong binding affinity for enamel, dentine and tartar, and during adsorption they have been shown to desorb stain components.…”

Section: Abrasivesmentioning

confidence: 94%