Evaluation of efficacy and adherence to INH preventive therapy in children at risk to develop active tuberculosis

Indumathi, C K; Kumar, Gurinder; Sethuraman, Aruna; Iyengar, Arpana

doi:10.1016/j.pid.2014.01.001

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…The National TB Program did not produce IEC materials to educate the public. Indumathi et al found that program uptake can be enhanced by adequate education at the start of the therapy and during subsequent follow ups [ 7 ]. This implies that, community education through the distribution of posters, fliers and pamphlets is necessary to improve awareness and program uptake.…”

Section: Discussionmentioning

confidence: 99%

“…A review of the Shurugwi IPT program, 2013 data, indicated that the majority of clients, eligible for IPT were not started on IPT. In 2013, three out 62 (5 %), zero out of 400 (0 %) and 4 out of 400 (1 %) of the eligible HIV positive clients were started in August, September and November respectively [ 7 ]. The target for IPT initiation is 100 % according to WHO and the National TB Program (NTP).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the isoniazid preventive therapy (IPT) program in Shurugwi District, Midlands Province, Zimbabwe, January 2013 to August 2014

et al. 2015

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BackgroundMidlands Province started implementing the Isoniazid (INH) preventive therapy (IPT) program in January 2013. Shurugwi and Gokwe North were the piloting district hospitals. In May 2014, four more districts hospitals (Gokwe South, Gweru, Kwekwe and Zvishavane) started implementing IPT. Shurugwi District decentralized the program to its rural health facilities in January 2014. A review of the Shurugwi IPT program, 2013 data, indicated that the majority of eligible clients were not started on IPT. None out of the 400 eligible clients were started on IPT in November against the 100 % target according to the World Health Organization and the National Tuberculosis (TB) Program. We conducted a study to evaluate the IPT program in Shurugwi District from January 2013 to August 2014.MethodsThe logical framework approach was used to evaluate inputs, processes, outputs and outcomes of the IPT program. An interviewer administered questionnaire was used to collect data from key informants. Checklists were used to collect data from IPT program records.ResultsSixteen health facilities were implementing IPT in Shurugwi District. All the facilities had TB screening tools and three did not have TB screening algorithms. The district experienced medicine stock outs in 2013. One formal training at district level and on job trainings in implementing health facilities were done. From January 2013 to August 2014, Shurugwi District screened 6794 antiretroviral (ART) clients for TB. Out of those screened, 5255 were eligible for IPT and 2831 (54 %) were started on IPT. A total of 700 clients had completed the IPT 6 month’s course by August 2014. The dropout rate due to INH toxicity and TB was 0.6 % (n = 18) and 0.3 % (n = 8) respectively. Fifty-three advocacy and community sensitization meetings were done. The program had no Information Education and Communication (IEC) materials.ConclusionThe IPT program in Shurugwi District achieved half its target. This could be due to inadequate formally trained staff, lack of IEC materials, inadequate advocacy and community sensitization, non-availability of the INH 300 mg single dose and inadequate INH 100 mg dose tablets in 2013. To improve the IPT program, there is need for routine advocacy, communication and social mobilization.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%