Evaluation of Efficacy diet supplemented with some local formulas on body weight and haematological parameters of rats

Abstract

Some local traditional formulas have been commonly used based on the information of their popularity in local markets for gaining weight. Hence, the aim of this study was conducted to evaluate the effect of some local prepared formulas (Mefataka, Kharaz El-Bakar, Tahwijat El-kortas El-Abiad) on body weight, hematological parameters and their efficacy in case of long-term consumption (8 weeks), using experimental animals. Forty two adult male albino rats were divided into seven groups (6 rats each), group (1) was fed on basal diet and kept as a control group, groups (2 and 3) were fed on basal diet supplemented with formula (1) "Mefataka", at the level of 10% and 15 % of the rats diet respectively. Groups (4 and 5) were fed on basal diet supplemented with formula (2) "kharaz El-Bakar", at the level of 10% and 15 % of the rats diet respectively. Groups (6 and 7) were fed on basal diet supplemented with formula (3) "Tahwijat El-kortas El-Abiad" at the level of 10% and 15 % respectively. The chemical composition of studied formulae Mefataka, Kharaz El-Bakar and Tahwijat El-kortas El-Abiad provided caloric value of 337.01, 346.44 and 395.7 K.cal/100g dried sample respectively. The results indicated that the body weight gain percent and feed efficiency ratio were increased significantly (P<0.05) in rats fed on their formulae, compared to the control group. Also, significant increase (P<0.05) in the levels of hematological parameters and leptin hormone were observed, however, there were no significant changes in liver and kidney functions, compared to the control group. Conclusion: The tested formulae increased the weight of rats without any harm on body systems. A trial of using these formulae on slim human seeking an increase in body weight is recommended.