Evaluation of efficacy of Vero cell-adapted, thermostable Newcastle disease vaccine in broilers

Siddique, Faisal; Mahmood, Muhammad Shahid; Hussaın, Iftikhar; Deeba, Farrah

doi:10.3382/japr/pfw055

Cited by 6 publications

(6 citation statements)

References 19 publications

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“…Initially, vaccines which require cold chains and administration expertise were developed, but in recent time, cheap thermostable vaccine with less expertise requirements is now available. One of these vaccines is NDV I-2 vaccine [ 6 ], and its use has been advocated for in rural poultry production [ 6 , 7 ]. Yet there seems not to be a continental spread of positive impact of this development on rural poultry production.…”

Section: Introductionmentioning

confidence: 99%

Awareness and antibody detection of Newcastle disease virus in a neglected society in Nigeria

et al. 2019

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Aim: This study aimed to assess the level of awareness of rural poultry farmers on vaccination and to detect Newcastle disease virus (NDV) antibody in local birds (LB) and eggs in Kwara State, Nigeria. Materials and Methods: Data on farmers' attitude, knowledge, practices, and experiences on ND mortality were obtained through an interview using a structured cross-sectional checklist. NDV antibodies were detected in sera and egg yolks of local chickens (LC) and guinea fowls (GF) using hemagglutination inhibition test. Results: A total of 83 interviewees, 287 sera and 121 egg yolk extracts, were examined. The study revealed that 98.8% (82/83) of the interviewee had never vaccinated their flock before. 90% of the interviewee had reported high mortality in birds within 1-6 months old, while the major clinical signs were cold (40.4%) and torticollis (30.8%). Evidences of LB exposure to wild-type NDV were confirmed by the detection of NDV antibodies in 20.8% and 0% of LC and GF, respectively. The mortality differences experienced in <1 and 1-6 months old LB could be explained by the presence of maternally-derived NDV antibody (49.6%) in egg yolk. Conclusion: The study showed that LB suffers from NDV as a result of LB keepers' ignorance and neglect by the government. This has limited local investment and subsequent contribution to gross domestic product. This study suggests that the key factors to the prevention of ND remain awareness creation about poultry vaccination, production of affordable vaccines, and availability/accessibility to veterinarian (or trained personnel).

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Section: Introductionmentioning

confidence: 99%

Awareness and antibody detection of Newcastle disease virus in a neglected society in Nigeria

et al. 2019

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“…Thermostable vaccines are less expensive and more significant in situations when cold chain temperature is not maintained. They may be kept between 2 and 8 degrees Celsius (Siddique et al, 2016). While freeze-dried vaccines should be maintained and stored at a low temperature in a refrigerator at 4 o C, even during vaccine transportation, thermostable vaccines have some tolerance to cold and hot environments.…”

Section: Managemental Practical and Technical Errors As A Cause Of Va...mentioning

confidence: 99%

Freezing, Heating and Some Factors Affecting Immune Response Induced by Inactivated Vaccines in Broiler Chickens

El Boraey,

Ayoub,

Shaaban

et al. 2024

Journal of Current Veterinary Research

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Poultry vaccines should have a specific storage temperature range to ensure their effectiveness. It is still unclear in Egypt, nevertheless, if these temperature ranges are rigidly specified as handling conditions or as recommendations. Large endemic and epidemic outbreaks of poultry illnesses frequently threaten Egypt's sizable conventional and exotic chicken industries. Although it is assumed in vaccine logistics that most of these safety measures are followed, handling vaccines within the specified temperature range is frequently not feasible. It is challenging to keep vaccines within a designated storage temperature range when they are being transported, according to earlier research. This is an issue not just in nations with weak cold chains but also in nations and areas with strong cold chains. Specifically, the chance of unintentionally being exposed to below-freezing conditions has been disregarded globally. This is a serious concern for vaccination consumers as well as the veterinarians who oversee vaccine usage. Because they cannot ensure the quality of vaccines whose storage temperature may have been beyond the prescribed range, veterinarians should advise consumers not to vaccinate birds with these vaccines. Additionally, the user is directly harmed in the uncommon case that a handling error impairs the quality of the vaccination.

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“…Most poultry species are vulnerable to NDV (Wajid et al, 2017). Numerous poultry species, including broiler, layer chickens, pigeons, ducks, turkeys, ostriches, peacocks, pheasants, double yellow headed parrots, waterfowls, and psittacine are infected with different NDV strains of the virus worldwide (Siddique et al, 2015).…”

Section: Taxonomy and Classificationmentioning

confidence: 99%

Isolation of newcastle disease virus from commercial broilers in district Abbottabad, Khyber Pakhtunkhwa, Pakistan

Saba,

Yousaf,

Dad

et al. 2023

Zoo Bot.

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The present study was carried out to isolate Newcastle disease virus in commercial broilers in district Abbottabad, KPK, Pakistan from January to June 2023. A total 60 broilers were swab sampled (cloacal and tracheal swabs) i.e. 120 swab samples were collected. The reverse transcription polymerase chain reaction procedure was done for isolation of Newcastle disease virus in National Reference Laboratory for Poultry Disease, Islamabad. Results revealed that out of total samples, only 5 tested positive for the Newcastle disease virus, indicating a prevalence percentage of 8.33%. Among the different areas surveyed, Qalandar Abad exhibited the highest occurrence of the Newcastle disease virus, with a prevalence rate of 20%. These findings highlight the geographical disparity in Newcastle disease virus prevalence and imply potential variations in risk factors or biosecurity measures among different regions within the district.

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Evaluation of efficacy of Vero cell-adapted, thermostable Newcastle disease vaccine in broilers

Cited by 6 publications

References 19 publications

Awareness and antibody detection of Newcastle disease virus in a neglected society in Nigeria

Awareness and antibody detection of Newcastle disease virus in a neglected society in Nigeria

Freezing, Heating and Some Factors Affecting Immune Response Induced by Inactivated Vaccines in Broiler Chickens

Isolation of newcastle disease virus from commercial broilers in district Abbottabad, Khyber Pakhtunkhwa, Pakistan

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