Evaluation of Frequency Adverse Drug Reactions in Tertiary Care Hospital of Kolkata, West Bengal, India

Abstract

(ADR) is a severe drawback of the therapeutics in the recent world. Pharmacovigilance is the practice of keeping records of these ADRs. The practice of pharmacovigilance is thus essential to decrease the incidence of adverse drug reaction occurring from different drugs. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. Correspondence

A retrospective study of adverse drug reactions in a tertiary care center

“…This was in concurrence with other similar studies by Adhikari A et al, Raja S et al, Venkatasubbaiah M, and Rani J. 13,14,17,19,20 However, Prashanthi B et al, observed anti-inflammatory agents and immunosuppressive drugs to be the most common cause of ADRs. 21…”

Analysis of spontaneous individual case safety reports reported at adverse drug reaction monitoring centre: tertiary care teaching hospital in South India

“…A drug or medicine is a pharmaceutical product of chemical substance used in the prevention, treatment, cure of disease or for the modification of physiological function or pathological state in the benefit of the recipient". 3,4 Drugs may be used for a limited duration, or on a regular basis for chronic disorders. Apart from all the benefits of the drugs, the adverse reactions and adverse events associated with them are most common.…”

“…Adverse drug reaction can be defined as "an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product". 3 They are usually preventable, cause of illness, which may require modifying the dosage regimen or discontinuing a medication or prolongation of hospitalization. But sometimes it results in disability or can be lifethreatening even cause death.…”

“…But sometimes it results in disability or can be lifethreatening even cause death. 3 At global level as well drug toxicity is playing as a major limitation in providing a good health care to patients by affecting health and economic burden. 2 The safety of drug prescribing has become a need of the hour topic in medicine because most of the important ADRs/AEs are caused by routinely prescribed and used medications.…”

“…When a study was conducted at South Indian tertiary care hospital, it was reported that 3.7% of the total hospitalized patients were suffering from ADR, among which 1.3% were fatal and 0.7% of the hospital admissions were due to ADRs. 3 ADRs can be reported either with single medication or with the multiple drug therapy and with each additional medication taken by the patient the harmful incidences of an ADR episode gets multiplied by 1.14 thereby increasing hospital admission and prolonged stay. 4 Hence, to counterfeit all the safety and economic challenges with use of drugs on health care system WHO as established "International Drug Monitoring Program" via a safety monitoring tool as pharmacovigilance.…”