Evaluation of Function of Mitral Valve After Homotransplantation in the Dog

Rastelli, G.C.; Berghuis, Jacob; Swan, H. J. C.

doi:10.1016/s0022-5223(19)33282-9

Cited by 27 publications

(5 citation statements)

References 6 publications

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“…Earlier experimental studies [1][2][3][4][5] and rare clinical trials 6,30 witnessed failure of the mitral homograft in most of the cases. The earlier clinical failures were attributed to inadequate valvular tissue conservation and technical difficulties.…”

Section: Discussionmentioning

confidence: 99%

Homograft mitral valve replacement: Five years' results

Kumar

Choudhary

Mathur

et al. 2000

The Journal of Thoracic and Cardiovascular Surgery

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Section: Discussionmentioning

confidence: 99%

Homograft mitral valve replacement: Five years' results

Kumar

Choudhary

Mathur

et al. 2000

The Journal of Thoracic and Cardiovascular Surgery

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“…The history of MA transplantation into the mitral position is completely different. It was pioneered in a canine model (Rastelli et al 1965, Vliet et al 1965, Hubka et al 1966. Clinical experience in limited series was also published (Cosgrove 1993, Pomar and Mestres 1993, Acar et al 1994a, 1996, Miyaghishima et al 2000.…”

Section: Discussionmentioning

confidence: 99%

One-Year Results From Cryopreserved Mitral Allograft Transplantation Into the Tricuspid Position in a Sheep Experimental Model

Mokráček

Čanádyová²,

Simunkova³

et al. 2015

Physiol Res

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Mitral allografts are still used only exceptionally in the mitral or tricuspid position. The main indication remains infectious endocarditis of atrioventricular valves for its flexibility and low risk of infection. The aim of our study was to evaluate 1-year results of mitral allografts transplantation into the tricuspid position in a sheep model. Mitral allografts were processed, cryopreserved, and transplanted into the tricuspid position anatomically (Group I – 11 animals) or antianatomically (Group II – 8 animals). All survivors (4 from Group I, and 3 from Group II) were checked at 3, 6, and 12 months by echocardiography with the exception of one survivor from Group II (which was examinated only visually). Examination throughout follow-up included for mitral allograft regurgitation and annuli dilatation. At postmortem, the papillary muscles were healed and firmly anchored to the right ventricular wall in all subjects. Transventricular fixation of the papillary muscles with buttressed sutures was proven to be a stable, reproducible, and safe method for anchoring mitral allograft leaflets. There were no significant differences between the two implantation methods. Annulus support of mitral allografts might be very useful in this type of operation and could prevent annular dilatation.

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“…. Time-course of change as a function of time of the z-coordinate of the tip and base of the anterior PM (APM) and the length of the APM throughout one cardiac cycle during the following conditions: [1] baseline, [2] reduced LV preload by vena caval occlusion ([/CO), [3] lowered reduced LV afterload by infusion of sodium nitroprusside (SNP), and [4]…”

Section: Methodsmentioning

confidence: 99%

“…4. Time-course of change of the z-coordinate of the tip and base of the posterior PM (PPM) and the length of the PPM for one typical cardiac cycle during with the following conditions: [1] baseline, [2] reduced preload by vena caval occlusion (VCO), [3] lowered afterload by infusion of sodium nitroprusside (SNP), and [4] tachycardia by atrial pacing. The z-coordinate of the PPM tip was nearly constant throughout the cardiac cycle compared with the z-coordinate of the PPM base and PPM length, which varied considerably (millimeters, mean -+ 1 standard deviation).…”

Section: ' Ih21iiii"mentioning

confidence: 99%

Papillary muscle–left ventricular wall “complex”

Komeda¹,

Glasson²,

Bolger³

et al. 1997

The Journal of Thoracic and Cardiovascular Surgery

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Papillary muscle length changed to keep the DTIP-MA distance constant such that the papillary muscle and left ventricular wall functioned together as a unit ("J-shaped complex"). These results provide a physiologic rationale for measuring DTIP-MA, define its potential surgical usefulness, and imply that using the entire length of the donor's papillary muscle (i.e., maintaining the entire J-shaped complex) is important in operations in which homograft or stentless xenograft mitral valves are used.

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Evaluation of Function of Mitral Valve After Homotransplantation in the Dog

Cited by 27 publications

References 6 publications

Homograft mitral valve replacement: Five years' results

Homograft mitral valve replacement: Five years' results

One-Year Results From Cryopreserved Mitral Allograft Transplantation Into the Tricuspid Position in a Sheep Experimental Model

Papillary muscle–left ventricular wall “complex”

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