Evaluation of Functionality and Biological Responses of Mytilus galloprovincialis after Exposure to Quaternium-15 (Methenamine 3-Chloroallylochloride)

Abstract

Abstract:Although the irritant effects of quaternium-15 have been established, little is known about the toxicological consequences induced by this xenobiotic on aquatic invertebrates. The present article reports toxicological, histological and physiological effects of quaternium-15 following the exposure of Mytilus galloprovincialis for 18 days at three different concentrations (0.1, 1.0 and 2.0 mg/L). The results demonstrate that at higher concentrations histological damages to M. galloprovincialis gills occur, like melanosis, light exfoliations, increase of mucus production and infiltrative inflammation. In addition digestive gland cells of M. galloprovincialis, were not able to perform the regulation volume decrease (RVD) owing to osmotic stress following the exposure to the preservative. Overall, this first study on quaternium-15 highlights that it can jeopardize both the morphology and vital physiological processes in marine invertebrates, depending on the duration of exposure and the concentration of the preservative, indicating that further studies are necessary to increase our knowledge about the effects of this substance, commonly added to our products of daily use.

Histopathological lesions and toxicity in common carp (Cyprinus carpio L. 1758) induced by copper nanoparticles

“…The sublethal concentration of heavy metal (i.e. NPs‐CuO, Nps‐Ag and Cd) can also lead into accumulation in aquatic organism and threatened the health of food chain (Torre, Trischitta, & Faggio, ).On the other hand, heavy metals may induce fish tissue lesions such as gill, liver, and skin (member cells) lesion (Pagano et al, ). Tissue lesions can change behavior, biology, and survival chance of aquatic organism such as fish (Mansouri et al, ).…”

Novel ABCB1 and ABCC Transporters Are Involved in the Detoxification of Benzo(α)pyrene in Thick Shell Mussel, Mytilus coruscus

“…The digestive cell type exhibits a well-established endo-lysosomal vacuolar system, such as heterolysosomes, heterophagosomes, and residual bodies, which takes part during the process of intra-cellular digestion (Dimitriadis et al, 2004). Additionally, the lysosomes of digestive cells are not only involved in the intra-cellular digestion of nutrients and antioxidant defenses (Faggio et al, 2016), but also regarded as an important organelle of organic pollutant and metal sequestration and detoxification (Marigómez et al, 2002;Pagano et al, 2016). Besides, the gills of filter-feeding bivalves are generally considered one of the major target organs for accumulating waterborne pollutants, either dissolved in or bound to particulate matter.…”

Interactive effects of coffee bean supplementation and waterborne zinc toxicity on growth performance, biochemical variables, antioxidant activity and zinc bioaccumulation in whole body of common carp, Cyprinus carpio L.

“…Fish are able to live in different aquatic ecosystems including metal‐contaminated environments and they exert metabolic mechanisms that help them for adaptation (Casella et al., ; Faggio, Fedele, Arfuso, Panzera, & Fazio, ; Fazio et al., ; Stephensen et al., ), for detoxification (Pagano et al., ; Sheehan, Meade, Foley, & Dowd, ) and for the antioxidant protection (Geret & Bebianno, ). SOD is an important defence enzyme that catalyses the dismutation of O 2 , which produces H 2 O 2 that is converted to H 2 O and molecular oxygen by CAT (Qu et al., ).…”

“…Fish are able to live in different aquatic ecosystems including metal-contaminated environments and they exert metabolic mechanisms that help them for adaptation (Casella et al, 2012;Faggio, Fedele, Arfuso, Panzera, & Fazio, 2014;Fazio et al, 2014;Stephensen et al, 2000), for detoxification (Pagano et al, 2016;Sheehan, Meade, Foley, & Dowd, 2001) and for the antioxidant protection (Geret & Bebianno, 2004). SOD is an important defence enzyme that catalyses T A B L E 3 Changes in some plasmatic biochemical parameters of common carp fed diets containing different levels of roasted coffee powder (RCP) and exposed to either 0.0 or 5.0 mg Zn/L for 6 weeks Means followed by different letters in the same column are significantly different at p < .05.…”