Evaluation of gastric motility of Phyllanthus emblica and Asparagus racemosus in cold stress induced gastric damage

Joshi, Shirish; Gajbhiye, Snehalata; Thatte, Urmila M

doi:10.18203/2319-2003.ijbcp20162463

Cited by 4 publications

(4 citation statements)

References 11 publications

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“…P. emblica and P. amarus extracts are reported to be gastroprotective against gastric ulcers and gastritis by enhancing gastric motility [ 126 , 127 ].…”

Section: Biological Activitiesmentioning

confidence: 99%

Chemical Components and Biological Activities of the Genus Phyllanthus: A Review of the Recent Literature

Nisar

Ahmed

et al. 2018

Molecules

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Medicinal plants have served humans since prehistoric times to treat various ailments. Both developed and underdeveloped countries rely on traditional systems of medication using natural sources from plants. Phyllanthus is one of the largest genus in the family Phyllanthaceae, comprising over 700 well known species cosmopolitan in distribution mainly in the tropics and subtropics. Phyllanthus species are being in constant used in traditional medications to cure an array of human diseases (constipation, inhalation related, arthritis, loss of appetite, injuries, conjunctivitis, diarrhoea, running nose, common cold, malaria, blennorrhagia, colic, diabetes mellitus, dysentery, indigestion, fever, gout, gonorrheal diseases of males and females, skin itching, jaundice, hepatic disorders, leucorrhea, vaginitis, menstrual irregularities, obesity, stomach pains, and tumors), confectionaries, food industry, and in some pesticides. Phyllanthus species are rich in diversity of phytochemicals e.g., tannins, terpenes, alkaloids, glycosidic compounds, saponins, and flavones etc. More in depth studies are a direly needed to identify more compounds with specific cellular functions to treat various ailments.

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“…P. emblica and P. amarus extracts are reported to be gastroprotective against gastric ulcers and gastritis by enhancing gastric motility [ 126 , 127 ].…”

Section: Biological Activitiesmentioning

confidence: 99%

Chemical Components and Biological Activities of the Genus Phyllanthus: A Review of the Recent Literature

Nisar

Ahmed

et al. 2018

Molecules

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“…Ranitidine 50 mg/kg Decrease in gastric motility and inhibition of production of some products of 5-lipoxygenase pathway [118] Embilica officinalis 270 Ranitidine 27mg/kg It deceased the gastric motility there by decreased the gastric erosions, [191] Decrease in the acid and pepsin secretion (antisecretory activity), Increase in the secretion of mucosal protective factors. Mucus secreted from the mucus neck cells covers the gastric mucosa thereby preventing physical damage and back diffusion of hydrogen ions [213] It acts as antioxidant by decreasing the gastric peroxidase activity and it could be due to the presence of Emblicanin A and B in its extract.…”

Section: Plantmentioning

confidence: 99%

Untitled

2024

OAJPR

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Peptic ulcer disease and its complications remain the cause of significant morbidity worldwide, representing a major burden for health care resources. Although potent anti-ulcer drugs are available, most of them produce several toxicities, thus emphasizing the need to search for new alternatives. As high as 80% of the world population depends on plantderived medicines for the first line of primary health care, reinforcing the theory that plant extracts can be good sources of new drugs. This review focuses to consolidate the evidence-based information on antiulcer plants used in Kerala accumulated in databases (

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“…It deceased the gastric motility there by decreased the gastric erosions, [191] . Decrease in the acid and pepsin secretion (antisecretory activity).…”

Section: Mangifera Indica 13mentioning

confidence: 99%

“…All test groups showed improvement in percentage of gastric emptying time which was found to be statistically significant (P≤0.01) as compared to control group, hot water extract showed highest improvement in gastric emptying. Thus they came to a conclusion that the mechanism of antiulcer activity of P. emblica and A. racemosus due to the gastric motility enhancing effect [191] .…”

Section: Phyllanthus Embilica Lmentioning

confidence: 99%