Evaluation of Genotoxic Effect of Marigold (Tagetes Erecta) Leaf Extract in Mice on Mitotic Chromosome

Abstract

In this study, 10% Marigold leaf extract was tested for possible genotoxicity by looking at mitotic aberrations. The study aimed to determine potential variations in the incidence of mitotic chromosomal abnormalities by comparing two groups: one group was treated with 10% Marigold leaf extract, and the other group received no therapy. The control group had a total of 37% mitotic chromosomal abnormalities, which included 24% structural abnormalities and 13% disruptive abnormalities. Conversely, On the other hand, the treatment group (who received a 10% Marigold leaf extract) exhibited a total of 53.00% mitotic aberrations, of which 25.00% were structural and 28.00% were disruptive. Compared to the control group, this percentage of anomalies was substantially (P<0.01) higher.10% of marigold leaf extract may be genotoxic.