2014
DOI: 10.4314/tjpr.v12i6.12
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Evaluation of Ginsenoside Rg1 as a Potential Antioxidant for Preventing or Ameliorating Progression of Atherosclerosis

Abstract: Purpose: To determine whether Rg1 inhibits H2O2-induced injury in human umbilical vein endothelial cells (HUVECs), an injury often regarded as a key early event in the development of atherosclerosis. Methods: Cell viability of HUVECs treated with pretreatment with different Rg1 concentrations (4,8, and 16 µmol/L)

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Cited by 2 publications
(2 citation statements)
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(29 reference statements)
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“…The assays were performed as described in our previous study. 9 Protein extraction, two-dimensional gel electrophoresis (2-DE) and protein digestion Two-dimensional gel electrophoresis (2-DE) was used in the present study to explore the potential mechanisms of Re against H 2 O 2 -induced oxidative stress in HUVECs. The cells were divided into two groups: H 2 O 2 (treated with 100 µmol per L of H 2 O 2 ) and Re (treated with 64 μmol per L Re + 100 µmol per L of H 2 O 2 ) groups.…”
Section: Ldh No Mda and Enzymatic Assaymentioning
confidence: 99%
“…The assays were performed as described in our previous study. 9 Protein extraction, two-dimensional gel electrophoresis (2-DE) and protein digestion Two-dimensional gel electrophoresis (2-DE) was used in the present study to explore the potential mechanisms of Re against H 2 O 2 -induced oxidative stress in HUVECs. The cells were divided into two groups: H 2 O 2 (treated with 100 µmol per L of H 2 O 2 ) and Re (treated with 64 μmol per L Re + 100 µmol per L of H 2 O 2 ) groups.…”
Section: Ldh No Mda and Enzymatic Assaymentioning
confidence: 99%
“…Loganin exhibited anti-inflammatory effect via inhibiting NF- κ B activation [ 21 ]. Uridine and ginsenosides Rg1 and Re were also found to have various effects, such as antioxidant and antifatigue [ 19 , 22 , 32 , 33 ].…”
Section: Discussionmentioning
confidence: 99%