Evaluation of growth factor independence 1 expression in patients with de novo  acute myeloid leukemia

Salarpour, Fatemeh; Goudarzipour, Kourosh; Mohammadi, Mohammad Hossein; Ahmadzadeh, Ahmad; Faraahi, Sara; Allahbakhshian, Atefeh; Farsani, Mehdi Allahbakhshian

doi:10.4103/jcrt.jcrt_129_17

Cited by 4 publications

(2 citation statements)

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“…The pathogenesis of this disease is complicated and remains obscure. Relevant studies have implied that the occurrence of this disease may also be related to multiple factors, such as the environment, body immune status in addition to genetic factors [17][18][19]. Chemotherapy is the optimal therapeutic regimen, but chemotherapy drugs often cause adverse side effects such as bone marrow suppression, anemia, nausea and vomiting, fatigue, and organ dysfunction, which seriously threaten the life safety of patients [20].…”

Section: Discussionmentioning

confidence: 99%

Analysis of the application value of functional status-based personalized nursing in clinical care for acute leukemia

2023

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To discuss the functional status-based personalized nursing in clinical care for acute leukemia. 175 patients with acute leukemia were divided into the conventional care group (patients within the group received routine care during chemotherapy for acute leukemia) and the observation group (patients within the group received functional status-based personalized care on the foundation of routine care) according to the method of random number table, and the mental status, quality of life, physical function status and complications during chemotherapy were compared between groups. Compared to the conventional care group following the intervention, the scores of self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were notably decreased in the observation group following the intervention. The scores of quality of life (QOL) and Karl Fischer Physical Functional Status Scale (KPS) were conspicuously increased, and the differences indicate statistical significance (p < 0.05); Compared with the conventional care group, the incidence of infection infectious fever, bleeding and ectopic liver function during chemotherapy in the study group were evidently reduced. The differences are statistically significant (p < 0.05). The functional status-based personalized nursing can effectively improve the mental status and quality of life, promote the physical function status, and effectively decrease the complications during chemotherapy in patients with acute leukemia, which is a safe and effective nursing model.

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Section: Discussionmentioning

confidence: 99%

Analysis of the application value of functional status-based personalized nursing in clinical care for acute leukemia

2023

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“…Research has shown that growth factor independence 1 (Gfi-1) plays major roles in tumorigenesis and cancer progression, including in chronic myeloid leukemia tumors [ 10 ], bone marrow cancer [ 11 ], and lung cancer [ 12 ]. The level of Gfi-1 is associated with drug resistance in tumors [ [13] , [14] , [15] ].…”

Section: Introductionmentioning

confidence: 99%

Gfi-1 modulates HMGB1-Mediated autophagy to overcome oxaliplatin resistance in colorectal cancer

Liu,

Zhang,

Zhang

et al. 2024

Heliyon

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Evaluation of LKB1 and Serine-Glycine Metabolism Pathway Genes (SHMT1 and GLDC) Expression in AML

Mezginejad

Mohammadi

Khadem

et al. 2020

Indian J Hematol Blood Transfus

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Evaluation of growth factor independence 1 expression in patients with de novo acute myeloid leukemia

Cited by 4 publications

References 0 publications

Analysis of the application value of functional status-based personalized nursing in clinical care for acute leukemia

Analysis of the application value of functional status-based personalized nursing in clinical care for acute leukemia

Gfi-1 modulates HMGB1-Mediated autophagy to overcome oxaliplatin resistance in colorectal cancer

Evaluation of LKB1 and Serine-Glycine Metabolism Pathway Genes (SHMT1 and GLDC) Expression in AML

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