Evaluation of Growth Performance, Blood Metabolites and Gene Expression Analysis in Egyptian Sheep Breeds, in Relation to Age

Ashour, G.; Gad, Ahmed Gomaa; Fayed, Ayat K.; Ashmawy, Neama A.; El-Sayed, Ashraf S. A.

doi:10.36380/scil.2020.wvj3

Cited by 4 publications

(6 citation statements)

References 38 publications

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“…The substantial discrepancy between TVC and TC is attributable to the different feed costs, which make up the majority of manufacturing costs. Feed prices also have an impact on overall costs as well as total variable costs [29].…”

Section: Discussionmentioning

confidence: 99%

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Analysis of Potential Genes and Economic Parameters Associated with Growth and Heat Tolerance in Sheep (Ovis aries)

Ibrahim

Al‐Sharif

Younis

et al. 2023

Animals

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This study explored the potential genes and economic factors that might be associated with growth and heat tolerance in two sheep breeds. Data on growth performance from the third month to six months of age were obtained based on records. In comparison to Aboudeleik lambs, Barki lambs developed considerably greater starting body weight, final body weight, final body weight gain, daily weight gain, and percentage increase in BW/month. Single nucleotide polymorphisms (SNPs) were found between lambs of the two breeds using PCR-DNA sequencing of CAST, LEP, MYLK4, MEF2B, STAT5A, TRPV1, HSP90AB1, HSPB6, HSF1, ST1P1, and ATP1A1 genes. Lambs from each breed were divided into groups based on detected SNPs in genes related to growth. The least squares means of the differentiated groups revealed a significant correlation of detected SNPs with growth and heat tolerance attributes (p ≤ 0.05). Barki lambs elicited greater total variable costs, total costs, total return, and net return values. The Barki sheep provided the best economic efficiency value when comparing the percentage difference between net profit and economic efficiency. Together with economic considerations, SNPs found may be used as proxies for marker-assisted selection of the best breed of sheep for traits related to growth and heat tolerance.

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Section: Discussionmentioning

confidence: 99%

“…Previous research examined the growth performance of sheep based on phenotypic characteristics [28,29]. However, no studies have previously examined sheep growth traits from an economic standpoint and by taking into account a candidate gene.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Potential Genes and Economic Parameters Associated with Growth and Heat Tolerance in Sheep (Ovis aries)

Ibrahim

Al‐Sharif

Younis

et al. 2023

Animals

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“…The increased body gain was the reflected in heavier final body weight of fast growing animals (49.9 Kg) compared to intermediate (40.7 Kg) and slow growing groups (30.8 Kg). The average body weight of Egyptian breeds is approximately 51 kg in Ossimi, 53 kg in Rahmani and 44 kg in Barki at marketing age [11,12,[21][22][23][24][25].…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, identification of genes underlying sheep growth performance would support worldwide efforts in increasing mutton production [10]. In this regard, gene expression profile was applied to detect growth performance of three Egyptian sheep breeds [11,12]. However, there is no available data that linked expression profile and both growth and carcass traits of Egyptian sheep.…”

Section: Introductionmentioning

confidence: 99%

Co-expression of candidate genes regulating growth performance and carcass traits of Barki lambs in Egypt

Ghanem¹,

Zayed²,

Mohamed³

et al. 2021

Preprint

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The aim of present study was to link the gene expression profile of selected candidate genes with blood profile, growth performance and carcass traits of Barki lambs. Thirty-eight Barki lambs were divided into 3 groups (fast, intermediate and slow growing) according to growth perfor-mance. Body tissues (muscle, liver and fat) were taken from for RNA isolation and Real-time PCR. The results indicated that, the final body weight hot carcass weight were heavier (P ≤ 0.05) in fast (49.9 Kg and 24.57) than intermediate (40.7 and 19.07 Kg) and slow (30.8 and 15.10 Kg) growing animals. The blood profile of total protein, total lipids, calcium, T3 and T4 hormones did not differ among sheep groups. Genes involved in protein biosynthesis (RPL7), fatty acid oxidation (CPT1) and lipolysis (FABP4) were up regulated in fast and intermediate growing lambs in all studied tissues. While, gene-regulating lipogenesis (ADIPOQ) was expressed simi-larly in fat and liver tissues, but increased its expression in muscle of fast and intermediate growing lambs. Expression of CAPN3 was increased in fast and intermediate growing compared to slow growing lambs. In conclusion, the current study providing an evidence for the im-portance of co-expression of these genes in main body tissues linked with growth performance of Barki lambs.

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“…Moreover, identi cation of genes underlying sheep growth performance would support worldwide efforts in increasing mutton production (Wang et al, 2015). In this regard, gene expression pro le was applied to detect growth performance of three Egyptian sheep breeds (Ashour et al, 2020;Miao et al, 2015). However, there is no available data that linked expression pro le and both growth and carcass traits of Egyptian sheep.…”

Section: Introductionmentioning

confidence: 99%

Co-Expression of Candidate Genes Regulating Growth Performance and Carcass Traits of Barki Lambs in Egypt

Ghanem

Zayed

Mohamed

et al. 2021

Preprint

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Sheep are considered one of the main sources of animal protein in Egypt while surviving harsh desert conditions. Therefore, the aim of present study was to link the gene expression profile of selected candidate genes with growth performance and carcass traits of Barki lambs. Thirty-eight Barki lambs were kept and fed individually after weaning till 12 months of age. Lambs were divided into 3 groups (fast, intermediate and slow growing) according to growth performance. Carcass traits were recorded directly after slaughtering. Three samples were taken from different body tissues (eye muscle, liver and fat tail) of each group, directly during slaughtering and stored at -80°C until RNA isolation. Real-time PCR was used to profile selected candidate genes (RPL7, CTP1, FABP4, ADIPOQ and CAPN3) and GAPDH was used as a housekeeping gene. The results indicated that, the final body weight was significantly (P ≤ 0.05) greater in fast (49.9 Kg) and intermediate (40.7 Kg) compared to slow growing animals (30.8 Kg). The hot carcass weight was heavier (P ≤ 0.05) in fast, intermediate (24.57 and 19.07 Kg) than low growing lambs (15.10 Kg). The blood profiles of T3 and T4 hormones showed no significant different among fast (1.1 ng/ml and 8.5 µg/dl), intermediate (0.6 ng/ml and 12.4 µg/dl) and slow growing lambs (1.0 ng/ml and 10.5 µg/dl). In addition, the total protein level was not differ in fast (5.94 g/dl), intermediate (6.52 g/dl) and slow growing lambs (6.9 g/dl). Genes involved in protein biosynthesis (RPL7), fatty acid oxidation (CPT1) and lipolysis (FABP4) were up regulated in fast and intermediate growing lambs in all studied tissues. While, gene-regulating lipogenesis (ADIPOQ) was expressed similarly in fat and liver tissues, but increased its expression in muscle of fast and intermediate growing lambs. Expression of CAPN3 was increased in fast and intermediate growing compared to slow growing lambs. In conclusion, the current study indicated a link between variation in gene expression profile in main body tissues with growth performance and carcass weight of Barki lambs, which induced by the genetic makeup however; this hypothesis required a large population for validation. In addition, the transcriptional profile of CPT1, FABP4 RPL7 and CAPN3 are linked with growth performance and carcass traits of Barki lambs, providing an evidence for the importance of co-expression of these genes in body main tissues involved in this process.

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Evaluation of Growth Performance, Blood Metabolites and Gene Expression Analysis in Egyptian Sheep Breeds, in Relation to Age

Cited by 4 publications

References 38 publications

Analysis of Potential Genes and Economic Parameters Associated with Growth and Heat Tolerance in Sheep (Ovis aries)

Analysis of Potential Genes and Economic Parameters Associated with Growth and Heat Tolerance in Sheep (Ovis aries)

Co-expression of candidate genes regulating growth performance and carcass traits of Barki lambs in Egypt

Co-Expression of Candidate Genes Regulating Growth Performance and Carcass Traits of Barki Lambs in Egypt

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