Evaluation of haematinic activity of Kumara Veeriya Kaantha Chendhuram in phenyl hydrazine induced Anemia in experimental rats

Abstract

The science of medicine is one of the fundamental requirements to well being of humans and their survival. Siddha system is one of the traditional systems of medicine. According to WHO, anaemia is one of the leading causes of death in worldwide. Anaemia is the most common blood disorder, affecting about one third of the global population. In classical Siddha literature, Kumara Veeriya Kaantha Chendhuram is one of the formulation mentioned in Anupoga Vaithiya Navaneetham – part I helps in overcoming iron deficiency anaemia. The ingredients of the formulation include Kaantham (magnetic oxide of iron) and Thara (Mollugo oppositifolia).The present study aims to evaluate haematinic activity by Phenyl hydrazine induced anaemia in animal models. The evaluation was carried out in Wistar albino rats. The effect of standard drug was comparable to those of the test drug. The blood parameters in animals treated with the test drug exhibited a highly statistical significant elevation when compared to control group.

Clinical evaluation of therapeutic efficacy of a Siddha herbo mineral formulation “Kumaara Veeriya Kaantha Chenduram’’ with “Nellikkai Legiyam” (internal) in the treatment of Iron Deficiency Anemia

“…(10) And the hemetinic activity of Kumaara Veeriya Kaantha Chenduram is proven by phenyl hydrazine induced anaemia in animal model which showed highly statistical significant elevation in blood parameters when compared to control group. (11) The Adjuvant drug Nellikkai legiyam, contains nellikkai (Phyllanthus emblica. L) one of the richest source of Vitamin C (Ascorbic acid) which enhances the absorption of iron in the trail drug.…”