Evaluation of Haemato-biochemical and Oxidative Stress Parameters in Dogs Affected with Gastroenteritis

Abstract

Gastroenteritis which is a common illness affecting all species of animals is much more severe in monogastric animals especially in dogs. The patho-physiology of gastroenteritis is quite diverse depending upon the specific etiology. The causes of gastroenteritis may be dietary, viral, bacterial, rickettsial, parasitic and miscellaneous. Gastroenteritis is characterized by varied clinical signs such as diarrhoea, vomition with or without blood, inappetance, lethargy, fever, anaemia and dehydration (Banja et al., 2002). These days oxidative stress is getting a lot of attention for various research studies as it plays very crucial role in the pathogenesis of different diseases. The oxidative stress occurs due to imbalance of production of reactive oxygen/nitrogen species or neutralizing antioxidant enzymes. Excessive production of free radicals and their metabolites, called

Evaluation of oxidative stress and efficacy of antioxidant therapy in dogs with haemorrhagic gastroenteritis

“…By the end of treatment, the mean value increased to 3537.07 ± 177.13U/L of plasma, which was significantly higher compared to the enzyme activity before treatment. Kataria et al (2020a) also reported reduced GSH-Px activity in diarrhoeic animals. Ighodaro and Akinloye (2018) described that the free radicals produced as a result of oxidative damage of lipids, proteins, RNA and DNA was neutralised by antioxidant enzyme glutathione peroxidase.…”