Evaluation of Hardware-related Geometrical Distortion in Structural MRI at 7 Tesla for Image-guided Applications in Neurosurgery

Dammann, Philipp; Kraff, Oliver; Wrede, Karsten H.; Özkan, Neriman; Orzada, Stephan; Mueller, Oliver; Sandalcioglu, I. Erol; Sure, Ulrich; Gizewski, Elke R.; Ladd, Mark E.; Gasser, Thomas

doi:10.1016/j.acra.2011.02.011

Cited by 38 publications

(48 citation statements)

References 36 publications

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“…For coregistration, high-resolution T1-weighted images from 7T MRI and from 3T MRI were skull-stripped using CBS Tools (http://www.cbs.mpg.de/institute/ software/cbs-hrt; Lucas et al, 2010;Bazin et al, 2012;Landman et al, 2013), and the stripped 7T structural image was coregistered onto the stripped 3T structural image and then once more onto the SPM8 T1 template image (Montreal Neurological Institute). These coregistered 7T structural images were obtained to confirm correct registration between the two experiment sessions and the absence of spatial distortion, which is known to increase with higher magnetic field strength (Dammann et al, 2011). The fMRI images were normalized to the standard SPM8 T1 template image and smoothed with an isotropic 3 mm full-width halfmaximum (FWHM) Gaussian kernel.…”

Section: Methodsmentioning

confidence: 99%

“…Among the available theories, we suggest that the concept of cross-temporal contingencies (Koechlin and Summerfield, 2008) was most suitable for generating the levels of cognitive hierarchies in both L2 and NL in the present study. (Desmond et al, 1998). In neuropsychological studies, patients with CN lesions were impaired in a controlled processing where an additional top-down process had to be intervened (Copland et al, 2000).…”

Section: The Pfcmentioning

confidence: 99%

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Functional Network Mirrored in the Prefrontal Cortex, Caudate Nucleus, and Thalamus: High-Resolution Functional Imaging and Structural Connectivity

Jeon

Anwander

Friederici

2014

Journal of Neuroscience

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Despite myriads of studies on a parallel organization of cortico-striatal-thalamo-cortical loops, direct evidence of this has been lacking for the healthy human brain. Here, we scrutinize the functional specificity of the cortico-subcortical loops depending on varying levels of cognitive hierarchy as well as their structural connectivity with high-resolution fMRI and diffusion-weighted MRI (dMRI) at 7 tesla. Three levels of cognitive hierarchy were implemented in two domains: second language and nonlanguage. In fMRI, for the higher level, activations were found in the ventroanterior portion of the prefrontal cortex (PFC), the head of the caudate nucleus (CN), and the ventral anterior nucleus (VA) in the thalamus. Conversely, for the lower level, activations were located in the posterior region of the PFC, the body of the CN, and the medial dorsal nucleus (MD) in the thalamus. This gradient pattern of activations was furthermore shown to be tenable by the parallel connectivity in dMRI tractography connecting the anterior regions of the PFC with the head of the CN and the VA in the thalamus, whereas the posterior activations of the PFC were linked to the body of the CN and the MD in the thalamus. This is the first human in vivo study combining fMRI and dMRI showing that the functional specificity is mirrored within the cortico-subcortical loop substantiated by parallel networks.

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Section: Methodsmentioning

confidence: 99%

Section: The Pfcmentioning

confidence: 99%

Functional Network Mirrored in the Prefrontal Cortex, Caudate Nucleus, and Thalamus: High-Resolution Functional Imaging and Structural Connectivity

Jeon

Anwander

Friederici

2014

Journal of Neuroscience

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“…However, MR images at 3 or 7 T may be altered by higher spatial distortions. 3 Thus, stereotactic targeting of the STN in patients with PD by direct visualization with ultra-high-field MRI with 3-or 7-T MR units may not be optimal. Furthermore, even at 7 T, the STN of NHPs cannot be delineated without a special contrast medium, such as the ultrasmall superparamagnetic iron oxide.…”

mentioning

confidence: 99%

“…3,25,31 Targeting of the STN is currently done stereotactically, which implies that the STN can be located from outside of the skull. Help from an anatomical atlas may be limited because of intersubject variations of such a small and deep brain structure.…”

mentioning

confidence: 99%

Three-dimensional SPACE fluid-attenuated inversion recovery at 3 T to improve subthalamic nucleus lead placement for deep brain stimulation in Parkinson's disease: from preclinical to clinical studies

Senova

Hosomi

Gurruchaga

et al. 2016

JNS

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abbreviatioNs DBS = deep brain stimulation; eSTN = electrophysiologically identified subthalamic nucleus; H&Y = Hoehn and Yahr; LEDD = levodopa equivalent daily dose; M12 = month 12 after implantation; NHP = nonhuman primate; PD = Parkinson's disease; SPACE = sampling perfection with application-optimized contrasts using different flip angle evolutions; STN = subthalamic nucleus; TEED = total electrical energy delivered; T1WI = T1-weighted imaging; T2WI = T2-weighted imaging; UPDRS = Unified Parkinson's Disease Rating Scale. . However, the procedure, which requires multimodal perioperative exploration such as imaging, electrophysiology, or clinical examination during macrostimulation to secure lead positioning, remains challenging because the STN cannot be reliably visualized using the gold standard, T2-weighted imaging (T2WI) at 1.5 T. Thus, there is a need to improve imaging tools to better visualize the STN, optimize DBS lead implantation, and enlarge DBS diffusion. methods Gradient-echo sequences such as those used in T2WI suffer from higher distortions at higher magnetic fields than spin-echo sequences. First, a spin-echo 3D SPACE (sampling perfection with application-optimized contrasts using different flip angle evolutions) FLAIR sequence at 3 T was designed, validated histologically in 2 nonhuman primates, and applied to 10 patients with PD; their data were clinically compared in a double-blind manner with those of a control group of 10 other patients with PD in whom STN targeting was performed using T2WI. results Overlap between the nonhuman primate STNs segmented on 3D-histological and on 3D-SPACE-FLAIR volumes was high for the 3 most anterior quarters (mean [± SD] Dice scores 0.73 ± 0.11, 0.74 ± 0.06, and 0.60 ± 0.09). STN limits determined by the 3D-SPACE-FLAIR sequence were more consistent with electrophysiological edges than those determined by T2WI (0.9 vs 1.4 mm, respectively). The imaging contrast of the STN on the 3D-SPACE-FLAIR sequence was 4 times higher (p < 0.05). Improvement in the Unified Parkinson's Disease Rating Scale Part III score (off medication, on stimulation) 12 months after the operation was higher for patients who underwent 3D-SPACE-FLAIRguided implantation than for those in whom T2WI was used (62.2% vs 43.6%, respectively; p < 0.05). The total electrical energy delivered decreased by 36.3% with the 3D-SPACE-FLAIR sequence (p < 0.05). coNclusioNs 3D-SPACE-FLAIR sequences at 3 T improved STN lead placement under stereotactic conditions, improved the clinical outcome of patients with PD, and increased the benefit/risk ratio of STN-DBS surgery.

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“…However, it reduces the total error of the procedure and thus promotes a more comprehensive understanding of therapeutic outcomes. In that regard, 2 recent studies 29,30 investigated possible issues for neurosurgical targeting due to higher geometric distortions at 7T. Without dissent, they reported relatively small distortions in the central brain regions and concluded that targeting is feasible with 7T imaging.…”

Section: Discussionmentioning

confidence: 99%

Direct Visualization of Anatomic Subfields within the Superior Aspect of the Human Lateral Thalamus by MRI at 7T

Kanowski¹,

Voges

Buentjen

et al. 2014

American Journal of Neuroradiology

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Evaluation of Hardware-related Geometrical Distortion in Structural MRI at 7 Tesla for Image-guided Applications in Neurosurgery

Cited by 38 publications

References 36 publications

Functional Network Mirrored in the Prefrontal Cortex, Caudate Nucleus, and Thalamus: High-Resolution Functional Imaging and Structural Connectivity

Functional Network Mirrored in the Prefrontal Cortex, Caudate Nucleus, and Thalamus: High-Resolution Functional Imaging and Structural Connectivity

Three-dimensional SPACE fluid-attenuated inversion recovery at 3 T to improve subthalamic nucleus lead placement for deep brain stimulation in Parkinson's disease: from preclinical to clinical studies

Direct Visualization of Anatomic Subfields within the Superior Aspect of the Human Lateral Thalamus by MRI at 7T

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