Evaluation of HBeAg and HBV viral load among general population of district Bannu, Khyber Pakhtunkhwa, Pakistan

Khan, Aamir; Khan, Muhammad Ismail; Khan, Salman A.; Rehman, Ata Ur; Ullah, Najeeb; Rehman, Ali; Khan, Jabbar; Ullah, Sarhad; Memon, Bilal Mustafa; Hamouda, Dalia G; Eltayeb, Lienda Bashier

doi:10.51847/zziecqodbe

J Adv Pharm Educ Res

2023

DOI: 10.51847/zziecqodbe

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Evaluation of HBeAg and HBV viral load among general population of district Bannu, Khyber Pakhtunkhwa, Pakistan

Aamir Khan¹,

Muhammad Ismail Khan²,

Salman A. Khan³

et al.

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2024

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Quantification of hepatitis B viral load in patients attending healthcare facilities in Gezira state, Sudan

Zakaria,

Eltaib,

Elsanousi

2024

F1000Res

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Background Hepatitis B virus (HBV) infection remains a significant global health challenge particularly in developing countries and regions. Gezira State, Sudan where prevalence and disease burden are high is an example of such regions. This study aimed to quantify HBV viral load among patients in Gezira State and assess the distribution of viral loads across demographic groups, including gender and age. Method A descriptive cross-sectional study was conducted between January 2022 and January 2023. Randomly selected 100 chronic HBV patients were enrolled from major healthcare facilities in Wad Medani, Gezira’s capital. Viral loads were measured using real-time PCR, and statistical analyses were performed to identify predictors of high viral load. Results The results revealed that the mean HBV viral load was 886,363 IU/ml (SD± 421,295), with a significantly higher mean in males (1,122,899 IU/ml) compared to females (531,559 IU/ml) (p< 0.0001). Viral loads ranged from 15 IU/ml to 35,474,488 IU/ml, with 37% of patients exceeding the WHO-recommended treatment threshold of 2,000 IU/ml. However, no significant association was found between viral load and age (p=0.939). Conclusion The study highlighted the need for gender-specific management strategies and the importance of HBV viral load quantification for effective public health intervention in Gezira State. Further research is recommended to explore HBV epidemiology in Sudan more comprehensively.

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Quantification of hepatitis B viral load in patients attending healthcare facilities in Gezira state, Sudan

Zakaria,

Eltaib,

Elsanousi

2024

F1000Res

View full text Add to dashboard Cite

show abstract

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Evaluation of HBeAg and HBV viral load among general population of district Bannu, Khyber Pakhtunkhwa, Pakistan

Cited by 1 publication

References 18 publications

Quantification of hepatitis B viral load in patients attending healthcare facilities in Gezira state, Sudan

Quantification of hepatitis B viral load in patients attending healthcare facilities in Gezira state, Sudan

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