“…Hepatitis B virus (HBV) is a hepatotropic DNA virus belongs to the family: Hepadnaviridae, genus: Orthohepadnavirus, and classified into four serotypes with 10 genotypes including different subtypes [ 1 , 2 ]. Although HBV infection requires species-specific host factors [ 3 , 4 ] and mainly affects human, the HBV and HBV-like virus can infect different types of mammals including chimpanzees, gibbons, gorillas, orangutans, woolly monkeys, pigs, and squirrels, with potential cross-species transmission among different hosts [ 5 , 6 ]. Recently, HBV-like virus has been identified in domestic cats [ 7 ].…”