Evaluation of heart work as a prediagnostic tool using the modified Windkessel model and different whole blood viscosity models

Suh, Sang Hyun; Kaptan, Yalın; Roh, Hyung-Woon; Kwon, Hyuck Moon; Lee, B. K.

doi:10.1504/pcfd.2012.048252

Cited by 1 publication

(2 citation statements)

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“…Flow rate in the left ventricle can be calculated with the mathematical fluid analysis shown in Fig. 7 by measuring blood pressure curves at two points in the peripheral arteries (brachial and radial arteries) 30). The blood viscosity model is essential to solve the problem of an increased burden of work on the heart, so further study will be needed to verify which viscosity model results are similar compared to in vivo results.…”

Section: Applications In the Cardiovascular Systemmentioning

confidence: 99%

“…7 by measuring blood pressure curves at two points in the peripheral arteries (brachial and radial arteries). 30) The blood viscosity model is essential to solve the problem of an increased burden of work on the heart, so further study will be needed to verify which viscosity model results are similar compared to in vivo results. However, this type of study might suggest the possibility of developing non-invasive devices for measuring WHO.…”

Section: Applications In the Cardiovascular Systemmentioning

confidence: 99%

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Computational Fluid Dynamics in Cardiovascular Disease

Lee

2011

Korean Circ J

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Computational fluid dynamics (CFD) is a mechanical engineering field for analyzing fluid flow, heat transfer, and associated phenomena, using computer-based simulation. CFD is a widely adopted methodology for solving complex problems in many modern engineering fields. The merit of CFD is developing new and improved devices and system designs, and optimization is conducted on existing equipment through computational simulations, resulting in enhanced efficiency and lower operating costs. However, in the biomedical field, CFD is still emerging. The main reason why CFD in the biomedical field has lagged behind is the tremendous complexity of human body fluid behavior. Recently, CFD biomedical research is more accessible, because high performance hardware and software are easily available with advances in computer science. All CFD processes contain three main components to provide useful information, such as pre-processing, solving mathematical equations, and post-processing. Initial accurate geometric modeling and boundary conditions are essential to achieve adequate results. Medical imaging, such as ultrasound imaging, computed tomography, and magnetic resonance imaging can be used for modeling, and Doppler ultrasound, pressure wire, and non-invasive pressure measurements are used for flow velocity and pressure as a boundary condition. Many simulations and clinical results have been used to study congenital heart disease, heart failure, ventricle function, aortic disease, and carotid and intra-cranial cerebrovascular diseases. With decreasing hardware costs and rapid computing times, researchers and medical scientists may increasingly use this reliable CFD tool to deliver accurate results. A realistic, multidisciplinary approach is essential to accomplish these tasks. Indefinite collaborations between mechanical engineers and clinical and medical scientists are essential. CFD may be an important methodology to understand the pathophysiology of the development and progression of disease and for establishing and creating treatment modalities in the cardiovascular field.

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Section: Applications In the Cardiovascular Systemmentioning

confidence: 99%

Section: Applications In the Cardiovascular Systemmentioning

confidence: 99%