Evaluation of hematological parameters in dyspepsia patients infected with Helicobacter pylori

Abstract

The data of dyspepsia and epigastric pain patients were derived from the hospital based registration system between 2020-2021. Logistic regression models were used to investigate the correlation between the onset of H. pylori infection and anemia.Results: Among 810 enrolled patients, there were 202 )24.9%( patients with H. pylori infection and 144 )17.8%( with anemia. The prevalence of anemia in the H. pylori )+( group was not statistically higher than the H. pylori )-( group after adjusting age, red blood cell count, serum ferritin, Original Articlemean corpuscular volume, platelet count, and mean corpuscular hemoglobin )p>0.05(. The level of hemoglobin was almost identical in both the H. pylori )+( group and the H. pylori )-( group )p>0.05(. Conclusion:The findings show that H. pylori infection may not be related to anemia in dyspepsia patients from the Central region of KSA.

Assessment of Helicobacter pylori cytotoxin-associated Gene A (Cag A) protein and its association with ferritin and vitamin B12 deficiencies among adult healthy asymptomatic residents in Sharjah, United Arab Emirates

“…However, the virulent oncoprotein CagA was found significantly correlated to both vitamin B12 and ferritin deficiencies. Several literature reviews have shown controversial studies related to H. pylori , ferritin and vitamin B12 deficiencies [ [40] , [41] , [42] , [44] , [45] , [46] , [47] , [48] , [91] , [92] , [93] , [94] ] while few studies have explored the correlation between the oncoprotein CagA and ferritin, vitamin B12 deficiencies [ 43 , 95 ]. In the current study, the association between H. pylori , CagA, ferritin and vitamin B12 in the UAE population was investigated for the first time on a large scale.…”