Evaluation of hepatoprotective activity of the ethanolic extract of leaves of Mimosa pudica linn in carbon tetrachloride induced hepatic injury in albino rats

Purkayastha, Ayan; Chakravarty, Pinaki; Dewan, Babul

doi:10.18203/2319-2003.ijbcp20160768

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…Research has shown that the leaves of M. pudica possess hepatoprotective activity, in a study conducted involving 14 Silymarin showed a significant decrease in the elevated levels of SGPT, SGOT, ALP, TB, and DB. This study shows the hepatoprotective effects of M. pudica [22,23] Wound healing activity…”

Section: Antihepatotoxic Activitymentioning

confidence: 79%

A Review on the Pharmacological and Traditional Properties of Mimosa Pudica

Hassan

Karunakaran

Abdulmumin

2019

Int J Pharm Pharm Sci

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Consumption of fruits and vegetables fight against oxidative damage by inhibiting or reducing free radicals and reactive oxygen species. Mimosa pudica is a perennial herb and belongs to the family Fabaceae. Epidemiological studies have shown that M. pudica contains metabolites such as phenols and flavonoid compounds which possess pharmacological properties such as antidiabetic, antimicrobial, antiulcer, antidepressants and anti-inflammatory. Ecological studies have shown that M. pudica grows in all types of soil which can survive in soil with low nutrient concentration. It usually requires disturbed soil to establish itself. It is commonly seen in the wastelands and along roadsides, which is an ethnomedical plant that may be used in managing various types of disease. Valuable information and literature on M. pudica are analysed and consulted using a different database such as Google Scholar, Google, Science Direct, Web of Science, Academic Journals and Pubmed. This review article summarises the pharmacological properties of M. pudica.

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Section: Antihepatotoxic Activitymentioning

confidence: 79%

A Review on the Pharmacological and Traditional Properties of Mimosa Pudica

Hassan

Karunakaran

Abdulmumin

2019

Int J Pharm Pharm Sci

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Section: Resultsmentioning

confidence: 99%

“…After 10 days, the control of hepatic parameters was observed, including ALT, AST, ALP, GGT and bilirubin, which was attributed to the presence of flavonoids in the extract. Purkayastha et al [91] also used a CCl 4 -induced hepatic injury model in rats to evaluate the effects of M. pudica leaf extract. The results showed that the ethanolic extract administered for 1 week protected the liver from CCl 4 damage at a dose of 400 mg/kg, as observed by serum parameters.…”

Section: Mimosa Pudica Lmentioning

confidence: 99%

Hepatoprotective Native Plants Documented in Brazilian Traditional Medicine Literature: Current Knowledge and Prospects

Arbo

Konrath

2022

Chemistry & Biodiversity

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The native flora of Brazil covers a large biodiversity of plants, some of which have important pharmacological properties. Ethnobotanical studies have established that the folk use of plants for hepatobiliary disorders is very common in Brazil. This review aimed to compile, describe and discuss the main native Brazilian medicinal plants used as hepatoprotective agents listed on 25 books by authors from various regions in the country. Based on the 153 species found, a comprehensive analysis of the most relevant scientific studies is presented, including Piper umbellatum, Echinodorus macrophyllus, Fevillea trilobata and Achyrocline satureioides. Some medicinal plants share both a large number of citations and scientific evidence to corroborate their hepatoprotective effects, including Solanum paniculatum, Baccharis crispa and Phyllanthus niruri, which could be of interest to develop new phytomedicines. Additionally, some active ingredients are indicated as being responsible for the liver protective effects described, particularly phenolic compounds (flavonoids, coumestans and lignans).

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“… [ 156 ] Mimosa pudica (Fabaceae) Ethanolic extract of Leaves Albino rats Carbon tetrachloride 400 mg/kg Total bilirubin↓, ALP↓, SGPT↓, SGOT↓ Anti-diabetic, antitoxin, antioxidant and wound healer. [ 157 ] Momordica charantia Linn. (Cucurbitac-eae) Hydro-alcoholic extract of Leaves Rats Carbon tetrachloride 100 & 200 mg/kg Total bilirubin↓, ALP↓, SGPT↓, SGOT↓ Antimicrobial [ 158 ] Momordica dioica (Cucurbita-ceae) Ethanolic and aqueous extract of Leaves Rats Carbon tetrachloride 200 mg/kg AST↓, ALT↓, ALP↓, total bilirubin (TB)↓ Used in head trouble, urinary calculi, tridosha, fever, asthma, bronchitis, high cough and piles.…”

Section: Hepatoprotective Potentials Of Medicinal Plants and Their Bi...mentioning

confidence: 99%

Medicinal herbs and their metabolites with biological potential to protect and combat liver toxicity and its disorders: A review

Islam Shawon,

Nargis Reyda,

Qais

2024

Heliyon

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Evaluation of hepatoprotective activity of the ethanolic extract of leaves of Mimosa pudica linn in carbon tetrachloride induced hepatic injury in albino rats

Cited by 5 publications

References 8 publications

A Review on the Pharmacological and Traditional Properties of Mimosa Pudica

A Review on the Pharmacological and Traditional Properties of Mimosa Pudica

Hepatoprotective Native Plants Documented in Brazilian Traditional Medicine Literature: Current Knowledge and Prospects

Medicinal herbs and their metabolites with biological potential to protect and combat liver toxicity and its disorders: A review

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