Evaluation of Hybrid Short Path Evaporation to Concentrate Lactic Acid and Sugars from Fermentation

Oliveira, Regiane Alves de; Komesu, Andrea; Rossell, Carlos Eduardo Vaz; Maciel, Maria Regina Wolf; Filho, Rubens Maciel

doi:10.15376/biores.13.2.2187-2203

Cited by 4 publications

(24 citation statements)

References 13 publications

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“…The generated vapour from each step, first condenses and then feeds the upstream evaporator. [63] Aspen simulations on this section demonstrated that this purification unit is sensitive to deviations in operating conditions because any failure in this section directly affects the quality or quantity of the final product.…”

Section: Discussionmentioning

confidence: 97%

Experimental methods in chemical engineering: Hazard and operability analysis—HAZOP

et al. 2022

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Hazards and operability analysis (HAZOP) is one of a dozen-structured Process Hazards Analysis (PHA) methodologies that assess risks associated with operating processes to mitigate their consequences. HAZOP applies to all six stages of process design from discovery to decommissioning. Industry massively adopted PHA methodologies as a consequence of several industrial disasters in the 1970s that increased society's scrutiny of chemical operations. HAZOPs are conducted by multidisciplinary teams that rely on a set of guide words in combination with the system parameters to identify deviations from the design intent. The team discuss the causes and consequences of deviations, and the project owner modifies the process accordingly. It relies on heuristics rather than algorithms, so the formal structure gives practitioners the false sense that the analysis is comprehensive. Academic institutions increasingly apply PHAs to experimental work, but the scope of a HAZOP is often ill-suited for this environment as it requires dedicated personnel with particular expertise. Here, we outline the essential features of a HAZOP analysis for early career researchers engaging in process development for conditions that include, for example, high temperature, high pressure, toxic compounds (Hg, phosgene, CO), and potentially explosive and flammable mixtures like organic peroxides. Web of Science indexed over 100 000 documents that mention safety in 2021 and assigned 1500 to chemical engineering. A bibliometric analysis grouped them into five clusters: (1) lithium ion batteries and nanoparticles, (2) fire, simulation, and combustion, (3) models, risk, systems, and techniques (including HAZOP), (3) models, risk, systems, and techniques (including HAZOP), (4) water treatment, and (5) mechanisms and thermal runaway.

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Section: Discussionmentioning

confidence: 97%

Experimental methods in chemical engineering: Hazard and operability analysis—HAZOP

et al. 2022

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“…plastics (i.e., polylactic acid (PLA)) (Demichelis et al, 2017). Recent market estimates have forecast significant growth in the demand for LA over the coming years due to its applicability in multiple industries and the role it plays in the production of PLA (Biddy et al, 2016;Castro-Aguirre et al, 2016;Alves de Oliveira et al, 2018;Ranjan and Baghel, 2018).…”

Section: Figurementioning

confidence: 99%

“…LA is a promising high-value intermediate produced during the pre-fermentation stage of two-stage AD and has been the focus of a few recent studies (Kim et al, 2016;Bastidas-Oyanedel and Schmidt, 2018;Demichelis et al, 2018;Bühlmann et al, 2021;Bühlmann et al, 2022a;Bühlmann et al, 2022b;Chenebault et al, 2022). LA (C 3 H 6 O 3 ) is a three-carbon organic acid which is generally sold as an 88 wt% solution which is expected to experience significant market growth to 1,960 kton by 2024/ 2025 valued at USD 9.8 billion (Alves de Oliveira et al, 2018;Presswire, 2018). The price of LA generally follows the price of starch and sugar feedstocks, and recently has reached around 3.0-4.0 USD•kg −1 (Alves de Oliveira et al, 2018).…”

Section: Anaerobic Production Of Lactic Acidmentioning

confidence: 99%

“…LA (C 3 H 6 O 3 ) is a three-carbon organic acid which is generally sold as an 88 wt% solution which is expected to experience significant market growth to 1,960 kton by 2024/ 2025 valued at USD 9.8 billion (Alves de Oliveira et al, 2018;Presswire, 2018). The price of LA generally follows the price of starch and sugar feedstocks, and recently has reached around 3.0-4.0 USD•kg −1 (Alves de Oliveira et al, 2018). PLA (marketed as a compostable bioplastic) is anticipated to play a significant role in the expansion of the LA market with forecasts estimating, by 2025, 50% of all globally produced LA will be utilised for PLA production (Carcus, 2012;Djukić-Vuković et al, 2019), likely somewhat driven by the market for compostable plastics.…”

Section: Anaerobic Production Of Lactic Acidmentioning

confidence: 99%

“…A large body of literature exists exploring LA fermentation and several reviews summarising the literature have been produced (Ghaffar et al, 2014;Alves de Oliveira et al, 2018;Eş et al, 2018). Fundamental research utilising waste streams for LA fermentation (Table 1) has identified that LA accumulation is promoted at low pH and short hydraulic retention time (HRT) with the separation of hydrolysis and fermentation leading to further improved productivity and yield (Demichelis et al, 2017).…”

Section: Anaerobic Production Of Lactic Acidmentioning

confidence: 99%

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Waste to Wealth: The power of food-waste anaerobic digestion integrated with lactic acid fermentation

Bühlmann,

Mickan,

Tait

et al. 2023

Front. Chem. Eng.

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Food waste (FW) costs the global economy $1 trillion annually and is associated with 8% of anthropogenic greenhouse gas emissions. Anaerobic digestion (AD) is an effective technology for recycling organic waste, including FW, for energy and nutrient recovery. Current major revenue streams for AD include the sale of biogas/power, gate fees, and digestate (fertiliser). However, subsidies provided by governments are a major profit driver for commercial facilities and are generally required for profitability, limiting its widespread adoption. Lactic acid (LA) is a high value intermediate of the AD process and literature evidence has indicated the recovery of LA can significantly boost the revenue generated from FW-AD. Moreover, FW fermentation naturally tends towards LA accumulation, promotion of LA producing bacteria, and inhibition of alternate competing microbes, making LA attractive for commercial production from FW. The integration of LA production and recovery into FW-AD could improve its economic performance and reduce the need for subsidy support, providing a platform for global adoption of the AD technology. However, challenges, such as 1) the low LA yield on FW, 2) seasonality of the FW composition, 3) unknown influence of LA recovery on downstream AD, and 4) impact of standard operational procedures for AD on upstream LA production, still exist making this focus area for future research. Even so, literature has shown the benefits of the LA-AD biorefinery, detailing improved process economics, increased FW utilisation, and elimination of subsidy support. Therefore, this review focuses on exploring the integrating LA production into AD by examining the current status of AD, LA integration strategies, challenges associated with LA production from FW, and identifies key challenges and considerations associated with downstream AD of fermented waste.

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Towards sustainable production of bio-based lactic acid via a bio-based technical route: Recent developments and the use of palm kernel cakes in the bioconversion

Rahim

Luthfi

Abdul

et al. 2022

BioRes

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The continued reliance on non-renewable fossil resources has led to serious environmental issues. In light of these concerns, the transition from non-renewable sources to more sustainable ones have been explored, as exemplified by the production of bio-based lactic acid via lignocellulosic biomass bio-refinery process. Malaysia, the second-largest producer of palm oil in the world, generates abundant, cheap, and underutilized oil palm biomass in the form of palm kernel cakes. Comprised of 50% fermentable hexose sugars, palm kernel cakes have emerged as an interesting feedstock substitute in the production of bio-based fine chemicals, e.g., lactic acid. This paper focuses on current work based on selected literature published in the 21st century on the exploitation of palm kernel cakes as a novel feedstock in bio-refinery processes after addressing the current global demand and potential commodity applications of bio-based lactic acid. It then discusses current research on potential lactic acid-producing microorganisms, with particular attention to bacteria, and different pretreatment methods for carbohydrate recovery from palm kernel cakes. It also highlights the potential of oil palm biomass, especially palm kernel cakes, as a promising commodity that contributes to sugar platforms in value-added products, e.g., biofuel, bioenergy, ethanol, acids, and fine chemicals.

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Evaluation of Hybrid Short Path Evaporation to Concentrate Lactic Acid and Sugars from Fermentation

Cited by 4 publications

References 13 publications

Experimental methods in chemical engineering: Hazard and operability analysis—HAZOP

Experimental methods in chemical engineering: Hazard and operability analysis—HAZOP

Waste to Wealth: The power of food-waste anaerobic digestion integrated with lactic acid fermentation

Towards sustainable production of bio-based lactic acid via a bio-based technical route: Recent developments and the use of palm kernel cakes in the bioconversion

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