Evaluation of immunostimulatory attributes of Asparagus racemosus and Withania somnifera supplemented diets in fish, Channa punctatus (Bloch, 1793)

Extraction, Quantification and Anti-Cancer Activity of Important Secondary Metabolite “Shatavarin-IV” from in vitro Callus Culture of Asparagus racemosus Willd.

“…[12] The root is the most important medicinal part of the A. racemosus which contains Shatavarin-I, IV and V. [13][14][15][16] Root extract had immunoadjuvant potential. [17,18] Conventionally extract of root was used to treat diarrhoea and dysentery due to its anti-diarrhoeal activity, [19] conjunctivitis, [20] spasm, chronic fevers and rheumatism, [21] anti-anaphylactic, [22] adaptogen, [23,24] anti-leishmanial activity, [25] anti-stress, [26,27] anti-ulcer, [28,29] anti-bacterial, [30] radioprotective agent, [31] Immunostimulatory, [32] Hypoglycemic activity, [33] Increased breast milk output. [34] Antiobesity, antihyperglycemic and antidepressive potentials on rat model.…”

Perturbations in Redox Status, Biochemical Indices, and Expression of XBP1s and NOX4 in the Livers of Channa Punctatus Following Exposure to Mancozeb

“…It is a bottom feeder, air-breathing fish, with yearlong availability, and is sensitive to changes in its environment. 16 The government of India also promotes the commercial production of murrel fishes (https://dst.gov.in/sites/default/files/Murrel.PDF). We assessed the effects of sublethal concentrations of MZ in the liver of C. punctatus by measuring biomarkers of oxidative stress [superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and lactate dehydrogenase (LDH) activity], liver injury [alkaline phosphatase (ALP), aspartate transaminase (AST), alanine transaminase (ALT), and total bilirubin (TB), along with reactive oxygen species (ROS) induction], and transcriptional profiling [spliced X-box binding protein (XBP1s) and NADPH Oxidase 4 (NOX4)].…”