Evaluation of Impedance on Biological Tissues Using Automatic Control Measurement System

Kil, Sang-Hyeong; Lee, Moo-Seok; Kim, Sangsik; Shin, Dong‐Hoon; Lee, Seong-Mo; Kim, Gun-do; Lee, Jong-Kyu

doi:10.7779/jksnt.2015.35.4.239

Cited by 1 publication

(2 citation statements)

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“…Currents with frequencies below 50 kHz cannot pass through cell membranes and can only traverse the extracellular fluid. However, as the frequency increases, the current penetrates the cell membrane, allowing it to pass through both intracellular and extracellular fluids [ 43 , 53 , 54 , 55 ]. Our goal was to measure the level of inflammation in the joint synovium of patients with RA.…”

Section: Validation and Resultsmentioning

confidence: 99%

“…BIA, a non-invasive and extensively utilized technology, accurately identifies body components by measuring liquid levels through microcurrent [ 42 ]. Impedance indicates the degree of difficulty for electric current to flow in the living body and is inversely proportional to the moisture content in tissues [ 43 , 44 ]. When intra-articular inflammation occurs in comparison to normal joints, extracellular fluid levels increase, resulting in a reduction in bioimpedance.…”

Section: Methodsmentioning

confidence: 99%

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Design of a Self-Measuring Device Based on Bioelectrical Impedance Analysis for Regular Monitoring of Rheumatoid Arthritis

Jeong,

Park,

Lee

et al. 2024

Sensors

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Rheumatoid arthritis (RA) is a chronic disease, in which permanent joint deformation is largely preventable with the timely introduction of appropriate treatment strategies. However, there is no consensus for patients with RA to monitor their progress and communicate it to the rheumatologist till the condition progresses to remission. In response to this unmet need, we proposed the design of a self-measuring device based on bioelectrical impedance analysis (BIA) for regular monitoring of inflammation levels. Twenty joints of both hands were measured to monitor trends in inflammation levels. Three electrodes were used to measure two joints of each finger. A central electrode was used for two consecutive measurements. A suitable form factor for the device was proposed for the vertical placement of the hand. To ensure the stability of measurements, an air cushion was incorporated into the back of the hand, hand containers were designed on both sides, and a mobile application was designed. We conducted a convergence-assessment experiment with five air pressures to validate the consistency and convergence of bioimpedance measurements. A heuristic evaluation of the usability around the product and mobile application was conducted in parallel by six subject matter experts and validated the design. This study underscores the significance of considering patients’ disease activity during intervals between hospital visits and introduces a novel approach to self-RA care.

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Section: Validation and Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%