2014
DOI: 10.1167/iovs.14-14118
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Evaluation of Inner Retinal Layers in Eyes With Temporal Hemianopic Visual Loss From Chiasmal Compression Using Optical Coherence Tomography

Abstract: Band atrophy leads to mRNFL and RGCL+ thinning, and INL thickening, and mRNFL and RGCL+ measurements are correlated strongly with VF loss. Segmented macular thickness measurements may be useful for quantifying neuronal loss in chiasmal compression.

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Cited by 86 publications
(93 citation statements)
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“…[30][31][32] There is evidence that OCT may be a useful predictive tool to assess potential visual field recovery in patients undergoing pituitary tumor resection (Fig. 6).…”
Section: Optical Coherence Tomographymentioning
confidence: 99%
“…[30][31][32] There is evidence that OCT may be a useful predictive tool to assess potential visual field recovery in patients undergoing pituitary tumor resection (Fig. 6).…”
Section: Optical Coherence Tomographymentioning
confidence: 99%
“…Advances in OCT technology have allowed segmentation of retinal layers and documentation of both RNFL and RGC layer loss in the macular areas of patients with optic atrophy (1-3). Secondary thickening and microcystic retinal edema (MRE) in the INL often are seen in such eyes (1)(2)(3). MRE in the INL initially was described in patients with multiple sclerosis (MS) and thought to represent direct involvement of the retina (3,4).…”
mentioning
confidence: 99%
“…MRE in the INL initially was described in patients with multiple sclerosis (MS) and thought to represent direct involvement of the retina (3,4). Reports were subsequently published of MRE in patients with other optic nerve, chiasmal, and optic tract lesions, showing that the finding is not specific for MS (2,(5)(6)(7)(8)(9). Although the exact mechanism for development of microcysts in the INL is still uncertain, MRE now is considered a secondary result of retrograde retinal degeneration (2,3,8).…”
mentioning
confidence: 99%
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“…Neste sentido, Monteiro et al além de demonstrarem que a CFNR-m e a CCG+ se correlacionam fortemente com a perda visual nos 16 pontos centrais do CV 24-2, também observaram que a camada nuclear interna (CNI) no hemicampo nasal é maior no pacientes do que nos controles, sendo identificados microcistos nessa camada uma porcentagem significativa dos pacientes e em nenhum dos controles [59] . Ainda faltam mais estudos para entender o significado clínico desse espessamento na CNI e a presença destes microcistos na CNI, os quais ocorrem em outras neuropatias do NO [60][61][62][63][64][65][66][67][68] .…”
Section: Específicosunclassified