Evaluation of Interleukin-10 -1082 G/A Gene Promoter Polymorphism among Hematologic Malignancies in Children

Abstract

Background: Hematological malignancies are forms of cancer that begin in the cells of the blood-forming tissue, such as the bone marrow. Childhood blood cancers are relatively rare but are still found to be the major cause of death in children aged 1-14years. Objective: The aim of the current work was to evaluate IL-10 (1082G/A) gene promoter polymorphism as a risk factor in children with hematological malignancies. Patients and Methods: This study included a total of 30 patients with newly diagnosed hematologic malignancies and 30 healthy children served as a control, attending at