The present study was investigated the biological activity of ethanolic leaf extract of Ipomoea carnea, as well as cool and boiled aqueous extracts for investigating toxic affect against, 2nd, and 4th instar larvae of the laboratory reared mosquito species Culex
quinquefasciatus after 24, 48 and 72 h of exposure. The tested larvae of Cx. quinquefasciatus were exposed to four concentrations (5, 2, 1 and 0.5 mg/ml) of crude ethanol leaf extract for different time durations. Results were demonstrated that ethanolic leaf extract at concentrations 5 and 2 mg/ml of I. carnea affected the mortality of second and fourth instar larvae it reached 100% after 24 h from treatments. Aqueous extracts of I. carnea leaves also lead to increased mortality rates of second and fourth larvae after 72h, at 50 mg/ml for cool and boiled aqueous extracts the mortality rates were increased into 90 and 95 % respectively. The present study showed that I. carnea leaves extracts have larvicidal activity against filarial vector mosquito Cx. quinquefasciatus.