Evaluation of joint toxicity of nitroaromatic compounds and copper to Photobacterium phosphoreum and QSAR analysis

Su, Limin; Zhang, Xujia; Yuan, Xing; Zhao, Yun-Tao; Zhang, Dongmei; Qin, Weichao

doi:10.1016/j.jhazmat.2012.09.065

Cited by 40 publications

(12 citation statements)

References 34 publications

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“…During recent times, heavy metals were focus of attention owing to their hazardous nature and subsequent toxicity studies. Various workers have assessed the combined toxicity of heavy metals (Su et al 2012;Qu et al 2013;Mochida et al 2006). It has been argued that the effects caused by combinations of various heavy metals may be more threatening and serious.…”

Section: Introductionmentioning

confidence: 99%

“…During last year, risk of environmental pollutants was assessed by a variety of biological models, but the Microtox Ò test can easily detect the presence of toxicants (Fulladosa et al 2005) by the light emitted by the P. phosphoreum in the standard laboratories. Different studies determined the toxicity of aromatic compounds, photolytic products and organic compounds (Parvez 2008;Jiao et al 2008;Su et al 2012). At the moment, the most suitable and delicate bioassay is the luminescent bacterium to assess the metal toxicities from industrial origin (Fulladosa et al 2004(Fulladosa et al , 2005Li et al 2001).…”

Section: Introductionmentioning

confidence: 99%

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Assessment of combined toxicity of heavy metals from industrial wastewaters on Photobacterium phosphoreum T3S

et al. 2016

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This research work is focusing on the toxicities of heavy metals of industrial origin to anaerobic digestion of the industrial wastewater. Photobacterium phosphoreum T3S was used as an indicator organism. The acute toxicities of heavy metals on P. phosphoreum T3S were assessed during 15-min half inhibitory concentration (IC50) as indicator at pH 5.5-6. Toxicity assays involved the assessment of multicomponent mixtures using TU and MTI approaches. The results of individual toxicity indicated that the toxicity of Cd, Cu and Pb on P. phosphoreum increased with increasing concentrations and there was a linear correlation. The 15-min IC 50 values of Cd, Cu and Pb were 0.537, 1.905 and 1.231 mg/L, respectively, and their toxic order was Cd [ Pb [ Cu. The combined effects of Cd, Cu and Pb were assayed by equivalent concentration mixing method. The results showed that the combined effects of Cd ? Cu, Cd ? Pb, Cu ? Pb, Cd ? Cu ? Pb were antagonistic, antagonistic and partly additive. The combined effect of three heavy metals was partly additive.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Assessment of combined toxicity of heavy metals from industrial wastewaters on Photobacterium phosphoreum T3S

et al. 2016

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“…The robustness of the models was confirmed by comparing the experimental and predicted values, and all the relative error values remain within 16% (Jin et al, 2014 ). Likewise, the joint toxicities of Cu (low, medium and high levels) with 11 nitroaromatic compounds (nitrobenzene, o -dinitrobenzene, m -nitrobromobenzene, p -nitrobromobenzene, o -nitroaniline, p -nitroaniline, p -nitrobenzoic acid, o -nitrophenol, m -nitrophenol, p -nitrophenol and 2,4-dinitrophenol) were studied by P. phosphoreum with developed QSAR analysis, there is a good agreement between the predicted values and experimental with R 2 = 0.764, P = 0.000, (Su et al, 2012 ). By drawing on the study of Su's, Zhang's, Su, Zhang, Li, Qin and Zhang ( 2019a ) work on the acute toxic effect of mixtures between metal Zn and above-mentioned 11 nitroaromatic compounds established robust QSAR models to predict the joint interaction when combined with Zn at low, medium, and high concentrations (Zhang et al, 2019a ).…”

Section: Methods Of Concentration Addition and Independence Actionmentioning

confidence: 98%

Mathematical Modeling Approaches for Assessing the Joint Toxicity of Chemical Mixtures Based on Luminescent Bacteria: A Systematic Review

Wang

Bai

et al. 2020

Front. Microbiol.

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Developments in industrial applications inevitably accelerate the discharge of enormous substances into the environment, whereas multi-component mixtures commonly cause joint toxicity which is distinct from the simple sum of independent effect. Thus, ecotoxicological assessment, by luminescent bioassays has recently brought increasing attention to overcome the environmental risks. Based on the above viewpoint, this review included a brief introduction to the occurrence and characteristics of toxic bioassay based on the luminescent bacteria. In order to assess the environmental risk of mixtures, a series of models for the prediction of the joint effect of multi-component mixtures have been summarized and discussed in-depth. Among them, Quantitative Structure-Activity Relationship (QSAR) method which was widely applied in silico has been described in detail. Furthermore, the reported potential mechanisms of joint toxicity on the luminescent bacteria were also overviewed, including the Trojan-horse type mechanism, funnel hypothesis, and fishing hypothesis. The future perspectives toward the development and application of toxicity assessment based on luminescent bacteria were proposed.

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“…Nitroaromatic compounds are an important group of chemicals which are widely used at present in various industries including agrochemicals, textile, and pharmaceutical industries (Su et al, 2012). They are highly resistant to degradation due to the presence of nitro groups .…”

Section: Biofilm-based Bioremediation Of Organic Compoundsmentioning

confidence: 99%

Bacterial biofilms and quorum sensing: fidelity in bioremediation technology

Mangwani

Kumari

Das

2016

Biotechnology and Genetic Engineering Reviews

103

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Increased contamination of the environment with toxic pollutants has paved the way for efficient strategies which can be implemented for environmental restoration. The major problem with conventional methods used for cleaning of pollutants is inefficiency and high economic costs. Bioremediation is a growing technology having advanced potential of cleaning pollutants. Biofilm formed by various micro-organisms potentially provide a suitable microenvironment for efficient bioremediation processes. High cell density and stress resistance properties of the biofilm environment provide opportunities for efficient metabolism of number of hydrophobic and toxic compounds. Bacterial biofilm formation is often regulated by quorum sensing (QS) which is a population density-based cell-cell communication process via signaling molecules. Numerous signaling molecules such as acyl homoserine lactones, peptides, autoinducer-2, diffusion signaling factors, and α-hydroxyketones have been studied in bacteria. Genetic alteration of QS machinery can be useful to modulate vital characters valuable for environmental applications such as biofilm formation, biosurfactant production, exopolysaccharide synthesis, horizontal gene transfer, catabolic gene expression, motility, and chemotaxis. These qualities are imperative for bacteria during degradation or detoxification of any pollutant. QS signals can be used for the fabrication of engineered biofilms with enhanced degradation kinetics. This review discusses the connection between QS and biofilm formation by bacteria in relation to bioremediation technology.

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Evaluation of joint toxicity of nitroaromatic compounds and copper to Photobacterium phosphoreum and QSAR analysis

Cited by 40 publications

References 34 publications

Assessment of combined toxicity of heavy metals from industrial wastewaters on Photobacterium phosphoreum T3S

Assessment of combined toxicity of heavy metals from industrial wastewaters on Photobacterium phosphoreum T3S

Mathematical Modeling Approaches for Assessing the Joint Toxicity of Chemical Mixtures Based on Luminescent Bacteria: A Systematic Review

Bacterial biofilms and quorum sensing: fidelity in bioremediation technology

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