Evaluation of left and right ventricular functions using conventional and tissue Doppler echocardiography in children with type 1 diabetes mellitus

Acar, Ömer; Epçaçan, Serdar; Üner, Abdurrahman; Ece, İ̇brahim; Doğan, Murat

doi:10.1515/jpem-2015-0453

Cited by 8 publications

(5 citation statements)

References 25 publications

(26 reference statements)

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“…The PW Tei index, a parameter computed from cardiac time intervals, seems to be an attractive method to assess cardiac function because it is relatively unaffected by anatomical disturbances or localized abnormalities of myocardium …”

Section: Discussionmentioning

confidence: 99%

Early anthracycline‐induced cardiotoxicity monitored by echocardiographic Doppler parameters combined with serum hs‐cTnT

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Early anthracycline‐induced cardiotoxicity monitored by echocardiographic Doppler parameters combined with serum hs‐cTnT

et al. 2017

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“…Tissue Doppler, atleast for some variables, is thought to be superior for assessing cardiac function compared with conventional echocardiography; however, the method is associated with some potential limitations as the results are sensitive to probe angle and noise interference and are associated with intraobserver and interobserver variability. [46][47][48] To evaluate the reproducibility and accuracy of the measurements, we therefore assessed intraobserver and interobserver variability and found the variabilities to be within an acceptable range. The women participating in this study were likely more healthy than women in general and not representative of all female populations.…”

Section: Experimental Considerationsmentioning

confidence: 99%

Cardiac Adaptations to High‐Intensity Aerobic Training in Premenopausal and Recent Postmenopausal Women: The Copenhagen Women Study

Egelund

Jørgensen

Mandrup

et al. 2017

JAHA

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BackgroundWe examined the role of menopause on cardiac dimensions and function and assessed the efficacy of exercise training before and after menopause.Methods and ResultsTwo groups of healthy premenopausal (n=36, 49.4±0.3 years) and postmenopausal (n=37, 53.5±0.5 years) women with no history of cardiovascular disease and with a mean age difference between groups of only 4 years were studied. Cardiac dimensions and systolic and diastolic function were determined by transthoracic echocardiography with tissue Doppler imaging and 2‐dimensional speckle tracking. Measurements were performed at baseline and after a 12‐week period of high‐intensity aerobic cycle training. LV internal diastolic diameter and LV mass were similar in the 2 groups at baseline and increased by ≈2% to 8% (P=0.04–0.0007) with training in both groups. Left atrial end‐diastolic and end‐systolic volumes were similar for both groups and increased by 23% to 36% (P=0.0006–0.0001) with training. Systolic function assessed by mean global strain was similar in both groups at baseline and increased by ≈8% (P=0.0004) with training in the postmenopausal group. LV displacement increased by ≈3% (P=0.04) in the premenopausal women only. Diastolic function assessed by E/A ratio was similar at baseline and increased by ≈7% (P=0.01) in the premenopausal group and 11% (P=0.0001) in the postmenopausal group with training.ConclusionsThese results suggest that training‐induced cardiac adaptations are preserved in the early postmenopausal phase. Furthermore, the hormonal changes associated with the menopausal transition do not appear to affect cardiac dimensions and function.Clinical Trial RegistrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT02135575.

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“…In children and adolescents with T1DM, studies showed variable results on subclinical LV diastolic dysfunction using conventional echocardiographic parameters or tissue Doppler . Also, tissue Doppler imaging studies have demonstrated subclinical systolic longitudinal dysfunction in adult and children patients with T1DM …”

Section: Introductionmentioning

confidence: 99%

Left ventricular functions in pediatric patients with ten years or more type 1 diabetes mellitus: Conventional echocardiography, tissue Doppler, and two‐dimensional speckle tracking study

Rakha

Aboelenin

2019

Pediatr Diabetes

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Background Cardiac dysfunction is a complication of type 1 diabetes mellitus (T1DM) with primary concern in adults. However, studies have evaluated left ventricle (LV) myocardial changes in pediatrics but not the long‐term effect of T1DM in such vulnerable age. Therefore, we assessed LV functions in pediatric patients with long‐duration T1DM using different echocardiographic modalities. Methods Between July 2015 and March 2016, 48 T1DM patients were prospectively compared to 35 healthy controls. Pediatric patients with T1DM for 10 years or more were included in the study. Patients were subjected to history taking, clinical examination, glycated hemoglobin (HbA1c), and microalbuminuria measurements. Moreover, conventional echocardiography, tissue Doppler, and 2D speckle tracking were performed to analyze LV functions. Results Mean age of patients was 15.5 ± 2 years, and mean T1DM duration was 11.7 ± 1.8 years. LV dimensions, EF and FS, and mass index did not statistically differ between groups, but E/E′ ratio was significantly higher in the diabetic group. Global longitudinal strain (GLS) and global circumferential strain (GCS) were significantly lower in diabetic patients compared with controls (P = 0.038; P = 0.001, respectively). Mean HbA1c was found to be a significant predictor of decreased GLS in the diabetic population (95% CI, 0.096‐0.244; P = 0.001) but not predicting GCS. Microalbuminuria had no significance in predicting strain. Conclusions Despite the long‐duration of affection with T1DM during childhood in our patients, alterations on LV myocardial function could not be detected either clinically or by conventional echocardiography. Tissue Doppler and speckle tracking could be used in the follow up of myocardial status in pediatric diabetic patients.

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Evaluation of left and right ventricular functions using conventional and tissue Doppler echocardiography in children with type 1 diabetes mellitus

Cited by 8 publications

References 25 publications

Early anthracycline‐induced cardiotoxicity monitored by echocardiographic Doppler parameters combined with serum hs‐cTnT

Early anthracycline‐induced cardiotoxicity monitored by echocardiographic Doppler parameters combined with serum hs‐cTnT

Cardiac Adaptations to High‐Intensity Aerobic Training in Premenopausal and Recent Postmenopausal Women: The Copenhagen Women Study

Left ventricular functions in pediatric patients with ten years or more type 1 diabetes mellitus: Conventional echocardiography, tissue Doppler, and two‐dimensional speckle tracking study

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