Evaluation of left atrial and ventricular remodeling in atrial fibrillation subtype by using speckle tracking echocardiography

Lu, Shirui; Liu, Hongyun; Sun, Jie; Zhang, Jun; Li, Li; Tang, Qiaoying; Liu, Yani; Deng, Youbin

doi:10.3389/fcvm.2023.1208577

Cited by 4 publications

(3 citation statements)

References 45 publications

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“…Still, this aspect could not be addressed from the present data set. We did not include patients with persistent AF, likely to fall closer to permanent rather than paroxysmal AF, since the total atrial fibrillation burden is associated with progressive LA structural remodeling and a decrease in LA reservoir function [ 28 , 29 ]. We did not have information on antiarrhythmic drugs other than beta-blockers in our data bank, not specifically focused on AF.…”

Section: Discussionmentioning

confidence: 99%

Rest and Stress Left Atrial Dysfunction in Patients with Atrial Fibrillation

Zagatina,

Rivadeneira Ruiz,

Ciampi

et al. 2023

JCM

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Background: Left atrial (LA) myopathy with paroxysmal and permanent atrial fibrillation (AF) is frequent in chronic coronary syndromes (CCS) but sometimes occult at rest and elicited by stress. Aim: This study sought to assess LA volume and function at rest and during stress across the spectrum of AF. Methods: In a prospective, multicenter, observational study design, we enrolled 3042 patients [age = 64 ± 12; 63.8% male] with known or suspected CCS: 2749 were in sinus rhythm (SR, Group 1); 191 in SR with a history of paroxysmal AF (Group 2); and 102 were in permanent AF (Group 3). All patients underwent stress echocardiography (SE). We measured left atrial volume index (LAVI) in all patients and LA Strain reservoir phase (LASr) in a subset of 486 patients. Results: LAVI increased from Group 1 to 3, both at rest (Group 1 = 27.6 ± 12.2, Group 2 = 31.6 ± 12.9, Group 3 = 43.3 ± 19.7 mL/m2, p < 0.001) and at peak stress (Group 1 = 26.2 ± 12.0, Group 2 = 31.2 ± 12.2, Group 3 = 43.9 ± 19.4 mL/m2, p < 0.001). LASr progressively decreased from Group 1 to 3, both at rest (Group 1 = 26.0 ± 8.5%, Group 2 = 23.2 ± 11.2%, Group 3 = 8.5 ± 6.5%, p < 0.001) and at peak stress (Group 1 = 26.9 ± 10.1, Group 2 = 23.8 ± 11.0 Group 3 = 10.7 ± 8.1%, p < 0.001). Stress B-lines (≥2) were more frequent in AF (Group 1 = 29.7% vs. Group 2 = 35.5% vs. Group 3 = 57.4%, p < 0.001). Inducible ischemia was less frequent in SR (Group 1 = 16.1% vs. Group 2 = 24.7% vs. Group 3 = 24.5%, p = 0.001). Conclusions: In CCS, rest and stress LA dilation and reservoir dysfunction are often present in paroxysmal and, more so, in permanent AF and are associated with more frequent inducible ischemia and pulmonary congestion during stress.

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Section: Discussionmentioning

confidence: 99%

Rest and Stress Left Atrial Dysfunction in Patients with Atrial Fibrillation

Zagatina,

Rivadeneira Ruiz,

Ciampi

et al. 2023

JCM

View full text Add to dashboard Cite

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“…In patients with established AF and normal LVEF, GLS was notably impaired during AF compared to sinus rhythm. 6 Additionally, a study found that indexed GLS measured during AF, adjusted for cycle length, significantly correlates with an increased risk of adverse outcomes, outperforming LVEF. 7 However, in a recent study, there was no evidence of systolic ventricular dysfunction based on myocardial strain in patients with idiopathic AF compared to healthy controls.…”

Section: Atrial Fibrillation Myocardial Work Strain Echocardiographymentioning

confidence: 99%

“…GLS has demonstrated predictive value for new‐onset AF across various clinical contexts, including post‐acute myocardial infarction or stroke presentations, 5 as well as within the general population. In patients with established AF and normal LVEF, GLS was notably impaired during AF compared to sinus rhythm 6 . Additionally, a study found that indexed GLS measured during AF, adjusted for cycle length, significantly correlates with an increased risk of adverse outcomes, outperforming LVEF 7 …”

mentioning

confidence: 99%