Evaluation of left ventricle diastolic dysfunction in ischemic heart disease by CMR: Correlation with echocardiography and myocardial scarring

Behairy, Noha; Homos, Mohamed D.; Ramadan, Ahmed; Gouda, Sherif

doi:10.1016/j.ejrnm.2014.07.007

Cited by 5 publications

(4 citation statements)

References 18 publications

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“…However, among patients with priormyocardial infarction, impaired relaxation was the only form of diastolic dysfunction observed. Though this category of patients was very few in this study, the pattern of diastolic dysfunction exhibited could be due to reduced myocardial compliance associated with ischaemia [24]. Majority of patients with progressive hypertensive heart disease in failure had preserved left ventricular ejection fraction.…”

Section: Discussionmentioning

confidence: 77%

Pattern, Precipitants and Short Term Outcome of Heart Failure Patients Managed at Federal Medical Centre Nguru, a Tertiary Health Centre in Yobe State Northeastern Nigeria

Baba¹,

Buba²,

Talle³

et al. 2018

IJCM

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Heart Failure (HF) is a syndrome characterized by typical symptoms (e.g. breathlessness, ankle swelling and fatigue) that may be accompanied by signs (e.g. elevated jugular venous pressure, pulmonary crackles and peripheral oedema) caused by a structural and/or functional cardiac abnormality, resulting in a reduced cardiac output and/or elevated intracardiac pressures at rest or during stress. Clinical studies investigating the aetiological patterns of heart failure in Sub-Saharan Africa (SSA) revealed that hypertension, cardiomyopathy and rheumatic heart disease account for more than two-thirds of cardiac disease cases. The objective of this study therefore is to assess the pattern, precipitating factors and short term outcome of heart failure among patients admitted into our hospital. Method: The study was a prospective cross-sectional type conducted among in patients with heart failure in the medical ward of the hospital. Results: A total of three and fifty four (354) subjects were recruited into the study, comprising one hundred and twenty nine males (36.4%) and two hundred and twenty five (63.4%) females. Majority of the patients were admitted in NYHA functional class IV. This however improved to class II at discharge though few were discharged in NYHA class III. Heart failure secondary to progressive hypertensive heart disease was the most common (39.0%) followed by peripartum cardiomyopathy (22.6%) while idiopathic dilated cardiomyopathy (11.0%) and rheumatic heart disease (7.3%) were the third and fourth causes of heart failure respectively. The most common precipitating factor for heart failure in this study was chest infection (44.9%). In conclusion, the study revealed that progressive hypertensive heart disease was the leading cause of heart failure, followed by peripartum cardi

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Section: Discussionmentioning

confidence: 77%

Pattern, Precipitants and Short Term Outcome of Heart Failure Patients Managed at Federal Medical Centre Nguru, a Tertiary Health Centre in Yobe State Northeastern Nigeria

Baba¹,

Buba²,

Talle³

et al. 2018

IJCM

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show abstract

“…The parameters measured are usually early and late maximal inflow velocities, in combination with early and late maximal myocardial tissue relaxation velocity. Overall agreement with echo-Doppler has been assessed in several studies, and most studies find overall good agreement, but CMR parameters are generally lower in amplitude and underestimate several parameters [ 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 ], likely because of the lower temporal frame rate with CMR in comparison with echo-Doppler. Good agreement has been shown between CMR postero-septal E/é and pulmonary capillary wedge pressure in patients with hypertension-related LV hypertrophy [ 71 ], but other CMR E/é positions were not correlated to pulmonary capillary wedge pressure.…”

Section: Resultsmentioning

confidence: 99%

Left Ventricular Diastolic Function Studied with Magnetic Resonance Imaging: A Systematic Review of Techniques and Relation to Established Measures of Diastolic Function

et al. 2021

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Purpose: In recent years, cardiac magnetic resonance (CMR) has been used to assess LV diastolic function. In this systematic review, studies were identified where CMR parameters had been evaluated in healthy and/or patient groups with proven diastolic dysfunction or known to develop heart failure with preserved ejection fraction. We aimed at describing the parameters most often used, thresholds where possible, and correlation to echocardiographic and invasive measurements. Methods and results: A systematic literature review was performed using the databases of PubMed, Embase, and Cochrane. In total, 3808 articles were screened, and 102 studies were included. Four main CMR techniques were identified: tagging; time/volume curves; mitral inflow quantification with velocity-encoded phase-contrast sequences; and feature tracking. Techniques were described and estimates were presented in tables. From published studies, peak change of torsion shear angle versus volume changes in early diastole (−dφ′/dV′) (from tagging analysis), early peak filling rate indexed to LV end-diastolic volume <2.1 s−1 (from LV time-volume curve analysis), enlarged LA maximal volume >52 mL/m2, lowered LA total (<40%), and lowered LA passive emptying fractions (<16%) seem to be reliable measures of LV diastolic dysfunction. Feature tracking, especially of the atrium, shows promise but is still a novel technique. Conclusion: CMR techniques of LV untwisting and early filling and LA measures of poor emptying are promising for the diagnosis of LV filling impairment, but further research in long-term follow-up studies is needed to assess the ability for the parameters to predict patient related outcomes.

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“…Addressing behavioral risk factors like obesity and overweight helps avoid most cardiovascular illnesses. The satiety hormone leptin reduces appetite and regulates energy (1) .…”

Section: Discussionmentioning

confidence: 99%

“…The satiety hormone leptin inhibits hunger and regulates energy balance, so the body does not elicit hunger reactions when it does not need energy (1,2) . One of the most essential adipocytokines, it regulates energy balance and appetite (3) .…”

Section: Introductionmentioning

confidence: 99%

Serum Leptin in Ischemic Heart Disease Patients with and without Significant Diastolic Dysfunction in Lean and Obese Patients; Cross-Sectional Study

2023

The Egyptian Journal of Hospital Medicine

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Background: Ischemic heart disease is a major cause of heart failure and has a poor prognosis. Addressing behavioral risk factors like obesity and overweight helps avoid most cardiovascular illnesses. The satiety hormone leptin reduces appetite and regulates energy. Aim of the study: Leptin levels in lean and obese patients with ischemic heart disease, with or without diastolic dysfunction, were compared. Methods and Patients: Between June 2019 and November 2020, 140 ischemic patients from Ain Shams University hospitals were included. History, examination, Duke Coronary Artery Disease score, Body Mass Index, serum leptin, and echocardiography were recorded. Patients were placed into four BMI and diastolic function groups plus the control group. A: lean ischemic patients without significant diastolic dysfunction, B: lean ischemic patients with diastolic dysfunction (II-IV), C: obese ischemic patients without significant diastolic dysfunction, Group D: obese ischemic patients with diastolic dysfunction, and E was a control group. Results: A positive correlation was seen between serum leptin and Duke score in all ischemia groups (n=140) (p<0.001). Serum leptin was higher in diastolic dysfunction groups (n=70) than in non-dysfunction groups (N=70) (Group B 25.7%, Group D 28.6% vs Group A 5.7%, Group C 8.6%, and Control Group (n=35) 0.0%). Conclusion: Leptin independently increases CAD risk. In CAD patients, elevated leptin was related to diastolic dysfunction.

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Evaluation of left ventricle diastolic dysfunction in ischemic heart disease by CMR: Correlation with echocardiography and myocardial scarring

Cited by 5 publications

References 18 publications

Pattern, Precipitants and Short Term Outcome of Heart Failure Patients Managed at Federal Medical Centre Nguru, a Tertiary Health Centre in Yobe State Northeastern Nigeria

Pattern, Precipitants and Short Term Outcome of Heart Failure Patients Managed at Federal Medical Centre Nguru, a Tertiary Health Centre in Yobe State Northeastern Nigeria

Left Ventricular Diastolic Function Studied with Magnetic Resonance Imaging: A Systematic Review of Techniques and Relation to Established Measures of Diastolic Function

Serum Leptin in Ischemic Heart Disease Patients with and without Significant Diastolic Dysfunction in Lean and Obese Patients; Cross-Sectional Study

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