Evaluation of Lipid Profile in Type-II Diabetes Mellitus with Obesity

Abstract

Abstracts Diabetes mellitus is a heterogeneous chronic metabolic disorder characterized by hyperglycemia and its lethal complications. Among the various types of diabetes, Type-II diabetes mellitus is the most prevalent variant and it is due to combination of insulin resistance and relative insulin deficiency due to pancreatic β cell failure. In this study we examined the serum lipid profile in obese Type II diabetics and compared with a control group who were obese but not diabetic. The mean TC, TG, HDL-c, FBS were 243.36±36.72, 201.97±55.44, 42.48 ± 9.2, 164.96 ± 16.8, 40.59±11.09 and 143.55 ± 38.68 respectively. In our study, the levels of TC, TG, LDL-c, VLDL-c were significantly increased while HDL-c levels did not show statistically significant difference in the two group.

Evaluation of leptin hormone and Tumor necrosis factor levels in patients with type two diabetes mellites

“…In patients with type 2 diabetes the risk of diabetic complications was strongly associated with raised blood pressure. Any reduction in blood pressure is likely to reduce the risk of complications, with the lowest risk being in those with systolic blood pressure less than 120 mm Hg (Stratton et al, 2000), also blood1 pressure1 is one of the risk1 factors affecting1 type 2 1diabetes patients according to the1 study (DeFronzo et al, 2015) (Chakrabarti et al, 2022;Gupta, 2016;Ouchi et al, 2022). In order to track a diabetic's glycemic management, glycated hemoglobin (HbA1c) levels are routinely monitored.…”