Evaluation of Liver Stiffness Measurement by Fibroscan as Compared to Liver Biopsy for Assessment of Hepatic Fibrosis in Children With Chronic Hepatitis C

Awad, M; Shiha, Gamal; Sallam, F; TAWAB, AMANY ABD EL

doi:10.21608/jesp.2013.93327

Cited by 1 publication

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“…Awad et al (2013) [ 12 ] conducted a prospective cohort study using 33 children with chronic hepatitis C who were admitted to the pediatric ward at Tanta University Hospital in Egypt. Based on their LSM score in kilopascals, patients were assigned an F score indicating disease severity.…”

Section: Reviewmentioning

confidence: 99%

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Implementing Better Standard Instruments for Detecting Cirrhosis in Hepatitis C Patients

Fagala,

Shpak

2023

Cureus

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An increasing number of hepatitis C diagnoses in the younger population could partly be due to the rising opioid epidemic and intravenous drug use. Using hepatic venous portal gradient (HVPG) and liver stiffness tests, this study investigates better early diagnostic markers in identifying cirrhosis-related complications compared to percutaneous liver biopsy in hepatitis C patients. Scholarly journal articles were surveyed using PubMed and MeSH terms. Articles published more than 15 years ago were excluded. Various databases from the New England Journal of Medicine and the Centers for Disease Control and Prevention were also referenced to support the hypothesis. There is substantial affirmation from cohort and clinical studies that transient elastography and HVPG can indicate advancing chronic inflammatory and fibrotic stages of cirrhosis in comparison to liver biopsy. Additionally, they are helpful in predicting overall mortality from complications such as esophageal varices. The use of liver stiffness measurements and HVPG appears to be equivalent and/or superior to liver biopsy in assessing advancing cirrhosis. As hepatitis C cases continue to rise, it is crucial to search for alternative methods to better suit the needs of the patients and to improve their overall prognosis and potential treatments. Liver biopsy as the gold standard for cirrhosis assessment is questionable when less invasive instrumental tools are available in practice that have been shown to predict progressing fibrosis.

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Section: Reviewmentioning

confidence: 99%

“…Awad et al (2013) [ 12 ] supported the notion that TE could be used to replace liver biopsy in many patients. Because the incidence rate of HCV is on the rise in the United States, this would save not only potential harm to patients but their costs as well.…”

Section: Reviewmentioning

confidence: 99%

Implementing Better Standard Instruments for Detecting Cirrhosis in Hepatitis C Patients

Fagala,

Shpak

2023

Cureus

View full text Add to dashboard Cite

show abstract

Evaluation of Liver Stiffness Measurement by Fibroscan as Compared to Liver Biopsy for Assessment of Hepatic Fibrosis in Children With Chronic Hepatitis C

Cited by 1 publication

References 0 publications

Implementing Better Standard Instruments for Detecting Cirrhosis in Hepatitis C Patients

Implementing Better Standard Instruments for Detecting Cirrhosis in Hepatitis C Patients

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