Evaluation of lung infiltration score to predict postural hypoxemia in ventilated acute respiratory distress syndrome patients and the lateralization of skin pressure sore

Tripathi, Mukesh; Pandey, Mamta; Nepal, Bharat B.; Hari, H.; Bhattarai, Balkrishna

doi:10.4103/0019-5359.56110

Cited by 5 publications

(5 citation statements)

References 24 publications

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“…To compare and assess the extent of radiologic infiltration, we used the lung scoring system18. Lung fields in the chest X-ray were divided into three zones by imaginary horizontal lines and further divided into medial and lateral halves using an imaginary vertical line between the midline (vertebral spines) and the vertical line along the outer margin of the rib cages.…”

Section: Methodsmentioning

confidence: 99%

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Predictors of Cardiogenic and Non-Cardiogenic Causes in Cases with Bilateral Chest Infiltrates

Lee

Park

et al. 2013

Tuberc Respir Dis

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BackgroundDifferentiating cardiogenic pulmonary edema from other bilateral lung diseases such as pneumonia is frequently difficult. We conducted a retrospective study to identify predictors for cardiogenic pulmonary edema and non-cardiogenic causes of bilateral lung infiltrates in chest radiographs.MethodsThe study included patients who had newly developed bilateral lung infiltrates in chest radiographs and patients who underwent echocardiography. Cases were divided into two groups based on the echocardiographic findings: the cardiogenic pulmonary edema group and the non-cardiogenic group. Clinical characteristics and basic laboratory findings were analyzed to identify predictors for differential diagnosis between cardiogenic and non-cardiogenic causes of bilateral chest infiltrates.ResultsWe analyzed 110 subjects. Predictors of cardiogenic pulmonary edema were higher brain natriuretic peptide (BNP) levels, lower C-reactive protein (CRP) levels on the day of the event (<7 mg/dL), age over 60 years, history of heart disease, and absence of fever and sputum. CRP on the day of the event was an independent factor to differentiate cardiogenic and non-cardiogenic causes of newly developed bilateral chest infiltrates. Also, the validity was comparable to BNP.ConclusionClinical symptoms (sputum and fever), medical history (dyslipidemia and heart disease), and laboratory findings (BNP and CRP) could be helpful in the differential diagnosis of patients with acute bilateral lung infiltrates in chest radiographs.

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Section: Methodsmentioning

confidence: 99%

“…Thus, each lung was divided into six segments. Based on the radiolucency of the lung infiltrates in the chest X-ray, scoring points (0 to 2; 0, normal alveolar picture; 1, patchy white infiltrates; 2, totally white infiltrates) were assigned to each segment18. Lung injury scores were not statistically different between the two groups.…”

Section: Methodsmentioning

confidence: 99%

Predictors of Cardiogenic and Non-Cardiogenic Causes in Cases with Bilateral Chest Infiltrates

Lee

Park

et al. 2013

Tuberc Respir Dis

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“…The readily available bedside chest X-ray is useful to map the inhomogeneity of the alveolar recruitment during PEEP in acute respiratory distress syndrome patients. The lung infiltration score for the different lung zones can map heterogeneity in lung recruitment [4]. This heterogeneity between the two lungs (lung infiltration score difference ≥3) was associated with postural hypoxemia when the worst lung was down in the lateral position and pre-disposed to skin sores on the worst lung side [4].…”

mentioning

confidence: 99%

“…The lung infiltration score for the different lung zones can map heterogeneity in lung recruitment [4]. This heterogeneity between the two lungs (lung infiltration score difference ≥3) was associated with postural hypoxemia when the worst lung was down in the lateral position and pre-disposed to skin sores on the worst lung side [4]. We opine that lung changes comprise a dynamic process in the ICU.…”

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confidence: 99%

Heterogeneity in ventilation during positive end-expiratory pressure

Tripathi

Pandey²

2010

Critical Care

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“…It is an essential issue to enhance skin cell growth during wound healing so in recent years, several models for skin epidermis and dermis reconstruction have been developed [8][9][10]. A number of experimental studies deal with new approaches to improve human skin cell growth using either physical, pharmacological or phytotherapeutic methods [11][12][13]. Tissue engineering is an effective method for developing skin substitutes and ameliorating the healing process.…”

Section: Introductionmentioning

confidence: 99%

Correction: Novel Biodegradable Porous Scaffold Applied to Skin Regeneration

Wang¹,

Chou²,

Wen³

et al. 2013

PLoS ONE

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Skin wound healing is an important lifesaving issue for massive lesions. A novel porous scaffold with collagen, hyaluronic acid and gelatin was developed for skin wound repair. The swelling ratio of this developed scaffold was assayed by water absorption capacity and showed a value of over 20 g water/g dried scaffold. The scaffold was then degraded in time-and dose-dependent manners by three enzymes: lysozyme, hyaluronidase and collagenase I. The average pore diameter of the scaffold was 132.568.4 mm measured from SEM images. With human skin cells growing for 7 days, the SEM images showed surface fractures on the scaffold due to enzymatic digestion, indicating the biodegradable properties of this scaffold. To simulate skin distribution, the human epidermal keratinocytes, melanocytes and dermal fibroblasts were seeded on the porous scaffold and the cross-section immunofluorescent staining demonstrated normal human skin layer distributions. The collagen amount was also quantified after skin cells seeding and presented an amount 50% higher than those seeded on culture wells. The in vivo histological results showed that the scaffold ameliorated wound healing, including decreasing neutrophil infiltrates and thickening newly generated skin compared to the group without treatments.

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Evaluation of lung infiltration score to predict postural hypoxemia in ventilated acute respiratory distress syndrome patients and the lateralization of skin pressure sore

Cited by 5 publications

References 24 publications

Predictors of Cardiogenic and Non-Cardiogenic Causes in Cases with Bilateral Chest Infiltrates

Predictors of Cardiogenic and Non-Cardiogenic Causes in Cases with Bilateral Chest Infiltrates

Heterogeneity in ventilation during positive end-expiratory pressure

Correction: Novel Biodegradable Porous Scaffold Applied to Skin Regeneration

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