Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment

Abstract

Purpose. To assess the predictive value of in ammatory blood biomarkers in rhegmatogenous retinal detachment (RRD) patients and its correlation with proliferative retinopathy (PVR) grade. Methods. 82 RRD patients and 1 : 1 age-and gender-randomly matched cataract patients as the control group were included. e clinical features and laboratory parameters of all participants were collected and recorded, and the comprehensive index of in ammatory blood and its correlation with PVR were calculated. Results. Monocytes and monocyte-to-high-density lipoprotein ratio (MHR) were signi cantly lower (P 0.005, P 0.044), while mean platelet volume (MPV), lymphocyte-to-monocyte ratio (LMR), and MPV-to-platelet ratio (MPR) were signi cantly higher in RRD patients as compared with the control group (P 0.013, P 0.019, P 0.037). LMR and MPR might be the predictors of RRD. e receiver operating characteristics analysis showed that the values of MPV, LMR, and MPR in RRD patients were 0.612, 0.606, and 0.594, respectively. PVR grade was not associated with in ammatory blood biomarkers. Conclusion. e increase in MPV, LMR, and MPR were associated with increased odds of RRD. LMR and MPR may be useful as inexpensive and e ortless biomarkers for assessing the occurrence of RRD.