Evaluation of mechanical, thermal and morphological properties of PLA films plasticized with maleic acid and its propyl ester derivatives

Enumo, Adalberto; Gross, Idejan P.; Saatkamp, Rodrigo H.; Pires, Alfredo T. N.; Parize, Alexandre Luís

doi:10.1016/j.polymertesting.2020.106552

Cited by 29 publications

(16 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast to other studies conducted on plasticization of polymers with di-carboxylic acids and their esters [ 31 , 32 , 63 ], this work does not show a clear link of plasticization to the reduction of the mechanical properties. For example, both succinic and maleic acid decreased the hardness by the same value with no significant difference despite having different plasticizing properties.…”

Section: Resultscontrasting

confidence: 99%

Investigating the Potential Plasticizing Effect of Di-Carboxylic Acids for the Manufacturing of Solid Oral Forms with Copovidone and Ibuprofen by Selective Laser Sintering

et al. 2021

View full text Add to dashboard Cite

In selective laser sintering (SLS), the heating temperature is a critical parameter for printability but can also be deleterious for the stability of active ingredients. This work aims to explore the plasticizing effect of di-carboxylic acids on reducing the optimal heating temperature (OHT) of polymer powder during SLS. First, mixtures of copovidone and di-carboxylic acids (succinic, fumaric, maleic, malic and tartaric acids) as well as formulations with two forms of ibuprofen (acid and sodium salt) were prepared to sinter solid oral forms (SOFs), and their respective OHT was determined. Plasticization was further studied by differential scanning calorimetry (DSC) and Fourier-transform infrared spectroscopy (FTIR). Following this, the printed SOFs were characterized (solid state, weight, hardness, disintegration time, drug content and release). It was found that all acids (except tartaric acid) reduced the OHT, with succinic acid being the most efficient. In the case of ibuprofen, only the acid form demonstrated a plasticizing effect. DSC and FTIR corroborated these observations showing a decrease in the glass transition temperature and the presence of interactions, respectively. Furthermore, the properties of the sintered SOFs were not affected by plasticization and the API was not degraded in all formulations. In conclusion, this study is a proof-of-concept that processability in SLS can improve with the use of di-carboxylic acids.

show abstract

Section: Resultscontrasting

confidence: 99%

Investigating the Potential Plasticizing Effect of Di-Carboxylic Acids for the Manufacturing of Solid Oral Forms with Copovidone and Ibuprofen by Selective Laser Sintering

et al. 2021

View full text Add to dashboard Cite

show abstract

“…As can be seen in Table , the glass transition temperature of the PLA decreases with the increase of the MBM quantity in the blend, suggesting that the molecule can act as a plasticizer. This behavior is analogous to that described previously by Enumo et al, using propyl maleate derivatives to plasticize PLA. To check if the MBM can really act as a plasticizer for PLA, a mixture in the 85/15 w/w (PLA/MBM) was prepared and pressed under the same conditions (180 °C, 2 ton for 1 min, twice) but in absence of water.…”

Section: Resultssupporting

confidence: 85%

Poly(lactic acid)/Poly(vinyl alcohol) Biodegradable Blends Using Monobutyl Maleate as a Plasticizer and Compatibilizer

Gross

Saatkamp

Sanches

et al. 2022

ACS Appl. Polym. Mater.

Self Cite

View full text Add to dashboard Cite

The Covid-19 pandemic situation has contributed to sparking discussions about an increase in packaging combined with the nonrecommendation of reuse. For this reason, many countries have encouraged the use of biodegradable polymers. In this study, blends of poly(lactic acid) (PLA) and poly(vinyl alcohol) (PVAL) were prepared at 80/20 (w/w) in the presence of specific amounts of monobutyl maleate (MBM) as a compatibilizer. All of these components are proven biodegradable. PLA/ PVAL/MBM blend films were obtained by thermopressing, and the thermal, mechanical, and morphological properties were evaluated by differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), tensile tests, stress relaxation, and scanning electron microscopy (SEM). DSC results suggest that MBM can act as a plasticizer, at least for the PLA matrix, reducing the T g from 60.2 °C (without MBM) to 23.5 °C in the case of the highest quantity of plasticizer (20%). Due to increase in macromolecular mobility, MBM also affects PLA crystallization. As a consequence of brittleness of the other samples, only those containing 15 and 20% of MBM (in PLA basis) did not fail the tensile and relaxation tests, showing more than 25% of elongation at break. Both the elastic and viscous parameters and the equilibrium modulus (E eq ) of the Maxwell−Wiechert mechanical system show lower values for the sample with higher MBM content. The SEM images show that the presence of the compatibilizer improves the adhesion between the PLA-rich phase and PVAL-rich phase.

show abstract

“…The characteristic absorption bands of each PLA functional group were found, corresponding to what is expected in the literature [45][46][47][48]. As shown in Figure 6, every spectrum contains an absorption band just below 3000 cm −1 corresponding to the C-H stretch and a weaker band at 1250 cm −1 corresponding to C-H deformation.…”

Section: Oxidation Index Based On Ftir Spectroscopysupporting

confidence: 80%

On the Mechanism of Electron Beam Radiation-Induced Modification of Poly(lactic acid) for Applications in Biodegradable Food Packaging

et al. 2022

View full text Add to dashboard Cite

Poly(lactic acid) (PLA) is a biodegradable polymer used for food packaging. The effects of electron beam radiation on the chemical and physical properties of amorphous PLA were studied. In this study, amorphous, racemic PLA was irradiated at doses of 5, 10, 15, and 20 kGy in the absence of oxygen. Utilizing electron paramagnetic resonance spectrometry, it was found that alkoxyl radicals are initially formed as a result of C-O-C bond scissions on the backbone of the PLA. The dominant radiation mechanism was determined to be H-abstraction by alkoxyl radicals to form C-centered radicals. The C-centered radicals undergo a subsequent peroxidation reaction with oxygen. The gel permeation chromatography (GPC) results indicate reduction in polymer molecular mass. The differential scanning calorimetry and X-ray diffraction results showed a subtle increase in crystallinity of the irradiated PLA. Water vapor transmission rates were unaffected by irradiation. In conclusion, these results support that irradiated PLA is a suitable material for applications in irradiation of food packaging, including food sterilization and biodegradation.

show abstract

Evaluation of mechanical, thermal and morphological properties of PLA films plasticized with maleic acid and its propyl ester derivatives

Cited by 29 publications

References 32 publications

Investigating the Potential Plasticizing Effect of Di-Carboxylic Acids for the Manufacturing of Solid Oral Forms with Copovidone and Ibuprofen by Selective Laser Sintering

Investigating the Potential Plasticizing Effect of Di-Carboxylic Acids for the Manufacturing of Solid Oral Forms with Copovidone and Ibuprofen by Selective Laser Sintering

Poly(lactic acid)/Poly(vinyl alcohol) Biodegradable Blends Using Monobutyl Maleate as a Plasticizer and Compatibilizer

On the Mechanism of Electron Beam Radiation-Induced Modification of Poly(lactic acid) for Applications in Biodegradable Food Packaging

Contact Info

Product

Resources

About