Evaluation of MEMS materials of construction for implantable medical devices

Kotzar, Geoffrey; Freas, Mark; Abel, Phillip B.; Fleischman, Aaron J.; Roy, Shuvo; Zorman, Christian A.; Moran, J. M.; Melzak, J. M.

doi:10.1016/s0142-9612(02)00007-8

Cited by 392 publications

(284 citation statements)

References 41 publications

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“…Implantable medical devices in biomedical applications [3], in particular, could take advantages in using this type of power supply since these batteries could insure a high life-quality in the patients requiring implantation, as there is no need of recharge or replacement.…”

Section: Introductionmentioning

confidence: 99%

Temperature dependence of an AlInP 63Ni betavoltaic cell

Butera

Lioliou

Krysa

et al. 2016

Journal of Applied Physics

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Abstract. In this paper the performance of an Al0.52In0.48P 63 Ni radioisotope cell is reported over the temperature range -20 °C to 140 °C. A 400 μm diameter p + -i-n + (2 μm i-layer) Al0.52In0.48P mesa photodiode was used as conversion device in a novel betavoltaic cell. Dark current measurements on the Al0.52In0.48P detector showed that the saturation current increased increasing the temperature, while the ideality factor decreased. The effects of the temperature on the key cell parameters were studied in

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Section: Introductionmentioning

confidence: 99%

Temperature dependence of an AlInP 63Ni betavoltaic cell

Butera

Lioliou

Krysa

et al. 2016

Journal of Applied Physics

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“…Most interestingly, the low per-unit cost is what business and consumers are looking for in every product and have been an undeniable trend (Grace, 1991). In addition, technologically, it also offers numerous materials that not only excellent mechanically for sensing and actuation (Bryzek et al, 2006), they are also biologically compatible (Kotzar et al, 2002). Undoubtedly, these MEMS based devices are the promising tools for outdoor ambulatory measurement and monitoring (Aminian & Najafi, 2004).…”

Section: Trends In Human Motion Measurementmentioning

confidence: 99%

“…Undoubtedly, these MEMS based devices are the promising tools for outdoor ambulatory measurement and monitoring (Aminian & Najafi, 2004). More interestingly, biomedical application is considered as one of the key new frontiers of MEMS based device development in the future with the worth of billions of dollars (Ko, 2007;Kotzar et al, 2002). In short, with the integration of elegant engineering, advanced instrumentation technology and continuous development in computing propels the art and science of human movement analysis beyond its basic description towards a more prominent role in surgery decision making, orthosis design, rehabilitation, ergonomics and sports (Curran, 2005).…”

Section: Trends In Human Motion Measurementmentioning

confidence: 99%

MEMS Biomedical Sensor for Gait Analysis

Wahab¹,

Bakar²

2011

Biomedical Engineering, Trends in Electronics, Communications and Software

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“…Given the desired small size of implantable devices, micromachining techniques will be essential. Although conventional silicon-based materials have been often used to microfabricate devices for in vivo applications, their general lack of biocompatibility is still an issue (34). To circumvent this problem, alternative nonconventional MEMS polymeric materials and coatings have been proposed to control surface hydrophilicity and minimize nonspecific protein adsorption (35).…”

Section: Microfabricationmentioning

confidence: 99%

Peer Reviewed: Responsive Drug Delivery Systems

Deo¹,

Moschou²,

Peteu³

et al. 2003

Anal. Chem.

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E ach person responds to a certain drug or combination of drugs in a unique manner. Drug absorption, distribution, and metabolism can vary widely among individuals, even within the same family (1), and especially for drugs that act upon a receptor or are involved in some other binding event within the body. The ability to monitor a disease's progression and respond to the unique changes in the body chemistry of each patient offers an unprecedented opportunity to deliver individualized medical care. An effective approach to individualized therapy involves ascertaining a marker molecule indicative of a disease state and subsequently delivering the type and dose of drug most appropriate for treatment (2). Using chemical biosensors to determine the levels of important marker molecules may serve to guide therapeutic regimens, thereby improving drug safety and efficacy. The need for this sort of responsive, individualized therapy has been a long-held, but largely unattainable, goal. The aim of this article is to describe the progress that has been made in the field of responsive drug delivery and to discuss the challenges that still need to be addressed.

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Evaluation of MEMS materials of construction for implantable medical devices

Cited by 392 publications

References 41 publications

Temperature dependence of an AlInP 63Ni betavoltaic cell

Temperature dependence of an AlInP 63Ni betavoltaic cell

MEMS Biomedical Sensor for Gait Analysis

Peer Reviewed: Responsive Drug Delivery Systems

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